PurposeThis study aimed to assess the bonding stability of three universal adhesives to a CAD‐CAM feldspathic ceramic with or without prior silane application.Materials and MethodsThe universal adhesives tested were Ambar Universal (FGM), Single Bond Universal (3M), and Ybond Universal (Yller). Scotchbond Multipurpose Plus (3M) was used as a control. The silane used was RelyX Ceramic Primer (3M). Microtensile bond strength (μTBS) to Vitablocs Mark II was measured after 24 h or 6 months of water aging (n = 20). Failure modes were observed through scanning electron microscopy, and pH and degree of C = C conversion (DC) of the adhesives were measured (n = 3). Data were analyzed using One‐, Two‐, and Three‐Way ANOVA.ResultsThe pH values differed significantly among the adhesives (P<0.001), while the DC was similar (P = 0.141). The universal adhesives showed significant differences in μTBS, with higher immediate results when using silane and lower results after aging. Notably, a significant decrease in μTBS was observed after 6 months when silane was applied. In contrast, the control adhesive exhibited consistent results between the 24‐hour and 6‐month storage periods. The universal adhesives showed a decrease in μTBS ranging from 25.5% to 40.1% after prolonged storage. Adhesive failures were predominant in all groups. The presence or absence of silane in the adhesive composition did not affect the bonding performance.ConclusionsThe application of a separate silane coupling agent improved the immediate bond strength of universal adhesives to CAD‐CAM feldspathic ceramic. However, this bond strength significantly decreased after 6 months of water aging. The bond strength remained stable for universal adhesives when applied without silane after 6 months of aging.This article is protected by copyright. All rights reserved