Effect of Direct-fed Microbials on Intestinal Villus Height in Broiler Chickens: A Systematic Review and Meta-Analysis of Controlled Trials

Heak, Chhaiden; Sukon, Peerapol; Kongpechr, Saijai; Tengjaroen, Bundit; Chuachan, Kanlaya

doi:10.3923/ijps.2017.403.414

Cited by 15 publications

(9 citation statements)

References 43 publications

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“…Ştef et al [47] have also demonstrated the positive effect of probiotics on the growth performances, gut health and disease prevention. Heak et al [20] have demonstrated that there have not been a significant positive effects of probiotics on the crypt depths bot in cecum and ileum (n=96 comparisons in research studies). We determined in this study that probiotics were more effective on the villus heights and crypt depths both in the ceca and ileum of chickens both infected and not.…”

Section: Discussionmentioning

confidence: 98%

“…The disease causes to death or sub-latent chronic disease. Even though chicken is not died, the chronic form and sub-clinic form of the disease may cause poor LBW, high FCR and secondary diseases [20,36] . In this study, the visible signs of coccidiosis infection in the ceca of chickens at 6 th day of post-infection has clearly demonstrated (Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Heak et al [20] have evaluated the results of 49 different studies made on the effect of probiotics on the epithelial tissue of the small intestines of chickens and only 32 of them have favored the DFM over control on villus heights. Nevertheless, the researchers has not been determined the positive effect of DFM on the crypt depth when checked the 96 studies made before.…”

Section: Discussionmentioning

confidence: 99%

“…Some of the bacteria used as probiotics are Lactobacillus, Pediococcus, Bacillus, Saccharomyces cerevisiae and Enterococcus faecium. Direct fed microbials (DFM) are include Aspergillus oryzae and Bacillus subtilis and also found to be useful [20] . In E. acervulina infected broilers, lower intestinal development of coccidiosis and lower oocyst production have been explained by enhanced local cell-mediated immunity when a Lactobacillus-based probiotic supplemented diet has been used [21] .…”

Section: Poultry Meatmentioning

confidence: 99%

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Probiyotiklerin Eimeria tenella İle Enfekte Broiler Piliçlerin Sağlık Durumu ve Verim Performansı Üzerine Etkileri

Erdogmus¹,

Gülmez²,

Findik³

et al. 2018

Kafkas Univ Vet Fak Derg

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A probiotic containing Pediococcus acidilactici and Bacillus subtilis (Smart ProLive) at a 1x10 7 CFU/mL dose in drinking water were given continuously from the d 14 to the end of the treatment (d 35) in broiler chickens. Experimental infection was produced by oral gavage of sporulated E. tenella oocysts at 14 th d of age. Feed consumption (FC), live body weight (LBW) and feed consumption rate (FCR) were measured at weekly basis. Villus height and crypt depth in cecum and ileum, and antibody titers in the blood were performed at 28-day-old. Probiotics appeared to be superior to salinomycin on the villus height and crypt depth of cecum and ileum (P<0.05). A numerical, but not significant (P>0.05) improvement on the LBW was determined at the groups of probiotic and salinomycin+probiotic than that of control and salinomycin groups. Nevertheless, FC and FCR results of the probiotic and salinomycin+probiotic groups were good than that of control and salinomycin groups. Probiotics were effective on the villus heights and crypt depths than that of salinomycin alone. Salinomycin appeared to be good only than control group in all the parameters. Not a significant difference from antibody titers was existed among the groups. Based on these results it can be concluded that a good source of probiotics can be used as natural antimicrobial growth promoters in replacement with forbidden anticoccidials in broiler rearing. Probiyotiklerin Eimeria tenella İle Enfekte Broiler Piliçlerin Sağlık Durumu ve Verim Performansı Üzerine EtkileriÖz Pediococcus acidilactici ve Bacillus subtilis içeren bir probiyotik (Smart ProLive) 14. günden 35. güne kadar içme suyu ile birlikte sürekli olarak 1x10 7 KOB/mL dozunda broiler civcivlere verildi. Deneysel enfeksiyon 14 günlük civcivlere sporlu E. tenella ookistleri ağız yoluyla verilerek yapıldı. Yem tüketimi, canlı ağırlıklar ve yemden yararlanma oranları haftalık olarak takip edildi. Sekum ve ileumda villus yüksekliği ve kript derinliği ile antikor titre analizi 28 günlük civcivlerde yapıldı. Probiotiklerin sekum ve ileumda villus yüksekliği ve kript derinliği üzerindeki olumlu etkisi salinomisinden daha üstün bulundu (P<0.05). İstatistiki önem ortaya çıkmamakla birlikte (P>0.05) canlı ağırlık artışı probiyotik ve probiyotik+salinomisin grubunda control ve salinomisin grubuna göre daha yüksek bulundu. Ancak, yem tüketimi ve yemden yararlanma konusunda probiyotik ve probiotik+salinomisin grupları kontrol ve salinomisin gruplarındakinden üstündü. Salinomisin tüm parametrelerde sadece control grubundan üstün olabildi. Antikor titreleri bakımından gruplar arasında fark gözlenmedi. Elde edilen bulgular ışığında iyi bir probiyotiğin kullanımı riskli ve direnç oluşumuna neden olabilecek antikoksidiyaller yerine doğal antimikrobiyal büyütme faktörü olarak kullanılabileceği öne sürülebilir.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Poultry Meatmentioning

confidence: 99%

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Probiyotiklerin Eimeria tenella İle Enfekte Broiler Piliçlerin Sağlık Durumu ve Verim Performansı Üzerine Etkileri

Erdogmus¹,

Gülmez²,

Findik³

et al. 2018

Kafkas Univ Vet Fak Derg

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“…Changes in the structure of the mucous membrane also take place when birds feed during intensely or experience hunger (Incharoen et al, 2010), are subject to manipulations (Yamauchi et al, 2010) involving addition of medical preparations of feed additives to their diet (Wijtten et al, 2012;Tsirtsikos et al, 2012;Incharoen, 2013;Cheled-Shoval et al, 2014) and stress situations (Varasteh et al, 2015;Marchini et al, 2016). At the same time, excessive impacts on the intestinal wall can cause pathological processes instead of adaptive reactions (Heak et al, 2017;Wang et al, 2018). A significant parameter for determining the efficiency of the digestive organs is the age formation of the nervous system (Goldstein & Nagy, 2008;Heanue et al, 2016;Chevalier et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Influence of the type of autonomic tone on the volume of the mucous membrane of the small intestine of laying hens

Tybinka

Blishch

Shchebentovska

2018

Regul. Mech. Biosyst.

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The connection between the separate structural parts of the mucous membrane of the small intestine of laying hens and the typological features of the autonomic tone were investigated. The studies were conducted on adult chickens of the cross-breed "Isa-Brown", which were divided into two groups: sympathicotonic chickens and sympathico-normotonic chickens, by the methods of electrocardiography and variation-pulsometry research. In the small intestine of the poultry of each group, the linear dimensions were determined first, and then the volume of the entire mucous membrane and its separate parts (villi, crypt, muscular plate), as well as the volume of connective tissue fibers in the crypt region. Research has shown that the villi account for ¾ of the volume of the entire mucous membrane. The volume of villi in the entire small intestine is more important in sympathico-normotonic chickens. This same poultry group has an advantage in the indicators of the volume of the muscular plate, but only in the duodenum and jejunum. In indicators of crypt volume, it turned out to be quite the opposite of the relationship with the typology of autonomous influences. In all studied intestines, the higher values of this indicator belong to the sympathotonic chickens. However, in terms of the volume of the entire mucous membrane, larger values still correspond to sympathico-normotonic chickens. Sympathicotonic chickens are inferior to them in the duodenum – at 1,005 mm3, in the jejunum – at 2,699 mm3 and in the ileum – only 78 mm3. Investigating the structure of the villi, we established that the volume of their epithelium in all three sections of the small intestine has higher values in the sympathico-normotonic chickens, and the larger volume of the lamina propria of the villi in the sympathicotonic chickens. At the same time, the connection with the type of autonomic tone is reflected in the ratio between the two layers of villi. In all three sections of the small intestine of sympathicotonic chickens, the ratio between the epithelium and the lamina propria was, on average, 65%/35%, or 2/1. In sympathico-normotonic chickens, this ratio varied and, on average, equalled 75%/25%, or 3/1. The increase in the tone of sympathetic centers contributes to the growth of volume both as the total amount of fibers of connective tissue, and also as separate elastic fibers in the area of crypt. According to the data,indicators of the sympathico-normotonic chickens are inferior to those of sympathicotonic chickens in all of the small intestine. It was also found that in both groups of poultry the volume of elastic fibers was approximately half the volume of all fibers of the connective tissue of the duodenum. In other sections of the small intestine, this figure was reduced to about ⅓. Consequently, the typological features of the autonomic tone, providing various trophic-regulatory effects on the mucous membrane of the small intestine, cause the formation of differences in its volume.

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Comparative effect of potentiated zinc oxide and antibiotic growth promoters on intestinal morphometry and nutrient digestibility in broiler chickens

Moog

Angeles

Merca

et al. 2021

Trop Anim Health Prod

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This study aims to determine the comparative effects of potentiated zinc oxide (pZnO) and antibiotic growth promoters (AGP) supplementation on intestinal morphometry and nutrient digestibility in broiler chickens. Four hundred straight-run day-old broiler chicks were randomly allotted to one of four dietary treatments replicated 10 times with 10 birds per replicate. Dietary treatments were: T1: Basal diets without AGP (negative control; NC), T2: Basal diets with 500 g/ton Maduramicin 10g and 500 g/ton Zinc bacitracin 150 (positive control; PC), T3: NC added with 150g/ton pZnO, and T4: PC added with 150g/ton pZnO in a 2x2 factorial design in RCBD. At days 18 and 35, 10 birds were randomly selected per treatment for morphometry of the duodenum, jejunum and ileum. At day 38, eight birds per treatment were used for the nutrient digestibility study. Results showed significant interaction effects (P<0.05) of AGP and pZnO supplementation on day 35 intestinal morphometry of duodenum's villi height and villi height: crypt depth, and ileum's crypt depth; apparent CODGE, AME, CP, DM and EE. Significant differences (P<0.05) with pZnO supplementation were only observed on feed intake and FCR of birds fed with pZnO at days 8-14 and fecal quality at days 0-7. Results of the study suggest that pZnO has the potential to replace AGPs without negatively affecting the intestinal morphometry, digestibility and growth performance of broiler chickens.

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Effect of Direct-fed Microbials on Intestinal Villus Height in Broiler Chickens: A Systematic Review and Meta-Analysis of Controlled Trials

Abstract: Records identif ied through database searching (PubMed and scopus) (n = 15, 987) Duplicates removed by title, author and journal (n = 5,520) Records after duplicates removed

Cited by 15 publications

References 43 publications

Probiyotiklerin Eimeria tenella İle Enfekte Broiler Piliçlerin Sağlık Durumu ve Verim Performansı Üzerine Etkileri

Probiyotiklerin Eimeria tenella İle Enfekte Broiler Piliçlerin Sağlık Durumu ve Verim Performansı Üzerine Etkileri

Influence of the type of autonomic tone on the volume of the mucous membrane of the small intestine of laying hens

Comparative effect of potentiated zinc oxide and antibiotic growth promoters on intestinal morphometry and nutrient digestibility in broiler chickens

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