Effect of dobutamine-induced myocardial ischemia on Doppler echocardiography after myocardial infarction

Wang, Chao-Hung; Cherng, Wen‐Jin; Hung, Ming‐Jui

doi:10.1016/s0002-8703(97)70026-7

Cited by 10 publications

(1 citation statement)

References 27 publications

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“…Similar effects and improved ventricular function have been seen in coronary surgery patients with preserved left ventricular performance (33). Conversely, impaired diastolic performance has been shown to be an early sign of dobutamine‐induced myocardial ischemia following myocardial infarction (34) and before percutaneous coronary angioplasty (10, 11). Moreover changes in regional diastolic function using pulsed Doppler myocardial imaging have been shown recently to be a sensitive marker of myocardial ischemia (14).…”

Section: Discussionmentioning

confidence: 99%

MR flow mapping of dobutamine‐induced changes in diastolic heart function

Paelinck

Lamb

Bax

et al. 2004

Magnetic Resonance Imaging

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Purpose:To evaluate the ability of MR flow mapping to measure changes in left ventricular filling during ␤-adrenergic stimulation. Materials and Methods:Mitral flow was measured in 10 healthy volunteers using conventional free breathing fastfield echo (FFE) with a spatial resolution of 2.7 ϫ 2.2 mm and a temporal resolution of 22 msec. The sequence was repeated during dobutamine infusion (20 g/kg/minute).Results: Stroke volume increased from a median of 99 mL (range: 68 -142 mL) (Note: values as presented are medians and ranges, throughout) to 114 mL (87-180 mL) (P Ͻ 0.05). Both early (E) peak filling rate (554 mL/second [433-497 mL] to 651 mL/second [496 -1096 mL/second]) (P Ͻ 0.05) and atrial (A) peak filling rate (238 mL/second [183-352 mL/second] to 341 mL/second [230 -538 mL/second]) (P Ͻ 0.05) increased. These changes, together with the increase in E acceleration peak and A deceleration peak, were consistent with facilitated myocardial relaxation. Conclusion:Conventional free breathing FFE has the ability to measure the effects of ␤-adrenergic stimulation on left ventricular filling.

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