Effect of donor cornea preservation in tissue culture and in McCarey-Kaufmann medium on corneal graft rejection and visual acuity

Abstract

In a retrospective study the rate of rejection and clouding of the donor cornea for other reasons was investigated in 230 penetrating keratoplasties performed between 1984-1986. Donor corneas were stored in McCarey-Kaufmann Medium (MK) at 4 degrees C or in a modified Minimal Essential Medium (MEM) at 31 degrees C. No statistical differences in rejection rate, cloudiness due to other causes or visual acuity was found between MEM- and MK-stored donor corneas.

Prospective, Randomized Clinical Evaluation of Optisol vs Organ Culture Corneal Storage Media

“…Compared with corneas stored in DexSol (Chiron Ophthalmics), Optisolstored corneas have been shown to be thinner after PKP. 1,14 Moll et al 15 and Rijneveld et al 16 could not find any difference between corneas stored in organ culture at 31°C and corneas stored in McCarey-Kaufman (MK) medium. De Beijer-Dominicus et al 17 reported that eyes transplanted with organ culture-stored corneas had lower visual acuities than eyes that had received corneas stored in MK medium.…”