Effect of dry period therapy on prevalence of mastitis in buffaloes in Haryana

Boora, Ashok; Yadav, Sarita; Devi, Parveena; Kumar, Anil; Singh, Inderjeet; Chahal, V P

doi:10.56093/ijans.v90i3.102414

Cited by 5 publications

(9 citation statements)

References 26 publications

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“…96 The 13 C NMR spectral data of the H 3 L ligand displayed distinctive signals for the -HC=N-and Ar-C-O groups, occurring at δ 165.74 ppm and δ 160.88 ppm, respectively. 97 Following complexation with Zn metal, these signals appeared a shift toward the deshielded region at δ 171.15 ppm and 167.26 ppm, respectively. This shift suggested that the lone pair electron density of nitrogen and oxygen atoms was directed toward the Zn atom, indicating the formation of the Zn (II) complex.…”

Section: H Andmentioning

confidence: 99%

Probing the variations of synthesis, antimicrobial activity, and optical properties of new lanthanide and transition metal complexes of salicylaldehyde‐dipropylenetriamine ligand

Ebqa'ai,

Reed,

Seni

et al. 2024

Applied Organom Chemis

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Due to their notable antimicrobial activity and optical properties, Schiff base ligands, along with their lanthanide and transition metal complexes, have seen extensive use in various applications. However, despite their potential, a comprehensive investigation into lanthanide and transition metal complexes using the same Schiff base ligand has not been reported to date. In this study, coordination compounds of lanthanide and transition metal ions were synthesized from the Schiff base ligand salicylaldehyde‐dipropylenetriamine. These complexes were characterized by elemental analysis, 1H and 13C NMR, mass spectroscopy, Fourier‐transform infrared spectroscopy ultraviolet–visible spectroscopy (UV–Vis), fluorescence spectroscopy, molar conductivity measurements, and thermogravimetric studies. Furthermore, the molecular structure of the Co (II) complex was determined by means of X‐ray crystallography. Thermogravimetric studies illustrated endothermic and non‐spontaneous degradation pathways of the complexes. UV–Vis spectra showed a new absorption band attributed to the ligand‐to‐metal charge transfer peak supporting the complexation between the ligand and metals. The lanthanide complexes exhibited distinctive luminescence emissions in the Sm (III), Tb (III), and Eu (III) complexes. This observation suggests that the ligand possesses the capability to absorb and efficiently transfer energy to the metal center of these lanthanide ions, thereby resulting in their characteristic luminescent properties. Additionally, antimicrobial investigations revealed that transition metal complexes generally exhibited antimicrobial activity against both gram‐positive and gram‐negative bacterial strains compared to lanthanide metal complexes, in most cases. However, it is noteworthy that the Dy (III) complex displayed the lowest minimum inhibitory concentration and minimum biocidal concentration values of 16 μg/ml against Staphylococcus epidermidis, indicating its potential as a candidate for the treatment of this pathogenic bacterium. The main purpose of this article is to investigate the variations in the synthesis and characterization of lanthanide and transition metal complexes utilizing the same Schiff base ligand suitable for applications in the pharmaceutical industry and optical material sciences.

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Section: H Andmentioning

confidence: 99%

Probing the variations of synthesis, antimicrobial activity, and optical properties of new lanthanide and transition metal complexes of salicylaldehyde‐dipropylenetriamine ligand

Ebqa'ai,

Reed,

Seni

et al. 2024

Applied Organom Chemis

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“…They also reported that the treated animals clinically improved significantly and remain longer in herd as compared to control cows. Boora et al (2020) studied effect caused by aDAT in SCM and IMI in 330 buffaloes and concluded that overall, 63.02 percent buffaloes suffering from IMI were totally cured in the dry-off period and cured 3.85 times greater as compared to those which did not receive the treatment.…”

Section: Table 4: Bacteriological Cure Rate Of Treatment Groups At Da...mentioning

confidence: 99%

Comparative therapeutic efficacy of intramammary Ceftiofur hydrochloride and Cefalonium during dry period in buffaloes

Kaushik,

Walwadkar,

Yadav

et al. 2023

Preprint

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Subclinical Mastitis (SCM) is mainly the major form of mastitis in modern livestock dairy animals. Antibiotic dry animal therapy proves to decrease risk of early lactation SCM. This study was designed to differentiate and compare efficacy of intramammary preparations i.e., Ceftiofur hydrochloride and Cefalonium during the dry period in buffaloes. The proposed work was carried out at ICAR- CIRB, Hisar, Haryana. Seventy-five buffaloes positive for SCM were randomized in three groups with 25 buffaloes in each group- two treatment groups (T2 and T3) and one untreated control group (T1). T2 group buffaloes were treated with drug Ceftiofur hydrochloride (500 mg) and T3 group with Cefalonium formulation (250 mg). Therapeutic efficacies of both the drugs were evaluated based on bacterial cure rates and Odd Ratios (OR). T2 treatment group showed better therapeutic response as compared to T3 groups the bacterial cure rate was 88% and 48% respectively, and the Odd Ratio (OR) of treatment group T2 was 0.0057 which was lower as compared to group T3 which was 0.0451.

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“…Schiff bases and their metal complexes are extensively utilized in numerous applications, such as chemosensors, 5,6 catalysis, 7,8 and intermediates in organic synthesis, 9,10 dye and pigments, 11 and others 12 . In the past decades, people have paid great attention to the research progress of Schiff‐base metal complexes due to their biological activities involving antibacterial, 13–16 antiproliferative, 17 antiapoptotic, 18,19 antimalarial and anti‐inflammatory activities 20–22 and as urease inhibitors. Schiff bases show a variety of biological activities, which may involve many reasons, but their structure containing azomethine or imine group is probably one of the reasons for their important role 23 .…”

Section: Introductionmentioning

confidence: 99%

Synthesis, crystal structure, and in vitro biological evaluation of bismuth (III) complexes incorporating pyrazinohydrazide‐derived Schiff bases

Li,

Qiu,

et al. 2024

Applied Organom Chemis

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Two new Schiff‐base bismuth (III) complexes were prepared by an equivalent reaction between Schiff‐base ligand and Bi (NO3)3•5H2O with the assistance of Mannitol. The chemical structures of the two complexes were characterized by spectroscopic studies (FT‐IR, NMR, and MS), elemental analysis, and single‐crystal X‐ray diffraction. The ligand‐to‐metal ion ratio was found to be 1:1 in the complexes. During the formation of the complexes, Schiff bases changed from the amidic forms to the iminol forms, and the resulting tautomers could coordinate with bismuth (III) ions to produce dinuclear BiIII complexes(1a and 2a). Structural analyses showed that each Bi (III) ion held a distorted capped octahedron geometry with a seven‐coordinate mode in two complexes. Screening in vitro biological activities revealed that two bismuth (III) complexes exhibited much higher antimicrobial and cytotoxic activity than their parent ligands. The cytotoxic activity of the complex(1a) was close to that of the known anticancer drug (Doxorubicin) by evaluating against SGC7901 cells, with the IC50 value 0.59 μM. The complex(1a) could effectively induce SGC7901 cell apoptosis and its oral acute toxicity for LD50 value was found to be 576 mg kg−1. The content of bismuth (III) in mitochondria was higher than that in the nucleus.

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Effect of dry period therapy on prevalence of mastitis in buffaloes in Haryana

Cited by 5 publications

References 26 publications

Probing the variations of synthesis, antimicrobial activity, and optical properties of new lanthanide and transition metal complexes of salicylaldehyde‐dipropylenetriamine ligand

Probing the variations of synthesis, antimicrobial activity, and optical properties of new lanthanide and transition metal complexes of salicylaldehyde‐dipropylenetriamine ligand

Comparative therapeutic efficacy of intramammary Ceftiofur hydrochloride and Cefalonium during dry period in buffaloes

Synthesis, crystal structure, and in vitro biological evaluation of bismuth (III) complexes incorporating pyrazinohydrazide‐derived Schiff bases

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