Effect of Elaeis guineensis (Jacq) leaf extracts on crude oil-induced genotoxicity in Wistar albino rats

Onakurhefe, P.; Achuba, F. I.; George, Betty; Okpoghono, Joel

doi:10.1016/j.sciaf.2020.e00280

Cited by 6 publications

(7 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The efficacy of the blended mixture had been established GC-MS analysis as well as genotoxicity studies. 44,45 Findings in the present study is a further contribution to the continual search for possible protection and solution to the dangers encountered by those in oil-spill prone areas who are at all times stands a risk of being exposed to petroleum-contaminated food substances. Also, this study reported a drop in hematological indices PCV, HB, and RBC in rats while there was an observed increase in WBC parameters due to COAF consumption.…”

Section: Resultsmentioning

confidence: 67%

See 1 more Smart Citation

Pretreatment with Oil Palm Leaf Extracts Confers Protection Against Crude Oil Adulterated Food (COAF)

2020

TJNPR

View full text Add to dashboard Cite

Honey 7 and Oil palm leaf powder. 26, 27 The oil palm leaf-a major agricultural waste have been identified to generate large tones of biomass and constitutes a high level of an environmental nuisance when left after the oil palm fruit has been harvested. 28,29 In a bid to contribute to the continual craving for re-use of agricultural waste into useful products; the present study explored the role of various solvent extracts of the oil palm leaf in conferring protection in rats consuming crude oil contaminated diets. Materials and Methods Materials The crude oil (Escravos blend) was obtained from Warri Refining and Petrochemical Company. Harvest of Elaeis guineensis leaves was done at Ovwor Mixed Secondary School Oil palm Plantation in Ughelli, Delta State, Nigeria. This was immediately rinsed with water to remove all traces of sand particles and unwanted debris. The leaf was identified at Forestry Research Institute of Nigeria, Ibadan with a voucher number of F101173. Chemicals of high-quality analytical grade were employed for analysis. Experimental animals Forty (40) mature albino Wistar male rats were purchased from the animal house of the

show abstract

Section: Resultsmentioning

confidence: 67%

“…This assertion is in agreement with earlier study by this same authors. 45 Also, the potency of the blended mixture relative to other extracts had been explained above. Also observed in this study is the petroleum-induced increase in liver function parameters in the liver and the serum of the experimental rats (Tables 3 and 4).…”

Section: Resultsmentioning

confidence: 96%

Pretreatment with Oil Palm Leaf Extracts Confers Protection Against Crude Oil Adulterated Food (COAF)

2020

TJNPR

View full text Add to dashboard Cite

show abstract

“…Ecological risk assessment entails evaluating the dangers that, in theory, exist for all living things in the various ecosystems that make up the environment due to the presence of substances introduced into the environment by humans [4]. It has been shown that crude oil can have a number of harmful impacts on health [26][27][28] and PCBs are found in crude oil production areas [22]. They have been proven to have substantial non-cancer health impacts on animals, including effects on the immune system, reproductive system, neurological system, endocrine system, and other health consequences [15].…”

Section: Ecological Risk Analysismentioning

confidence: 99%

Health risk assessment of polychlorinated biphenyls exposure from inland rivers sediments in Warri-South, Warri, Delta State

Amurun,

Okpoghono,

Anunuso

2024

Ovidius University Annals of Chemistry

View full text Add to dashboard Cite

The health risk of polychlorinated biphenyls (PCBs) exposure from Ugbuwangue, Ugbori and Edjeba rivers sediments in Warri-South, Warri, Delta State was investigated. Nine sediment samples were collected; three samples each along the course of the different rivers. The sediment samples were Soxhlet extracted with acetone/dichloromethane/nhexane (1:1:1 v/v). A total of 28 PCBs were quantified using gas chromatography coupled with mass spectrometry detector. The concentration of the 28 PCBs ranges from 178.76-1398.29 ng g−1 for Ugbuwangue river, 224.81-685.19 ng g-1 for Ugbori river and 539.33-7858.3 ng g−1 for Edjeba river. The concentration of 12 PCBs were recorded for dioxin-like PCBs ranged from 0.08-401.52 ng g−1 (Ugbuwangue river 0.13 to 223.11 ng g−1, Ugbori river 0.08 to 153.39 ng g−1 and Edjeba river 0.32 to 401.52 ng g−1), while the concentration of 16 non-dioxin-like PCBs were recorded ranging from 0.13-4245.71 ng g−1 (Ugbuwangue river 0.18 to 386.47 ng g−1, Ugbori river 0.13 to 111.98 ng g−1 and Edjeba river 0.31 to 4245.71 ng g−1). The ecological risks of the nine sediment samples were investigated and it ranges from 25.52 – 1122.616 with Edjeba river sediment having the highest ecological risk while Ugbuwangue river sediment has the least ecological risk.

show abstract

“…This organic chemical is a major source of revenue for many countries and raw material for many industries [1][2][3]. All activities, such as production, distribution, and utilization of petroleum have been reported to expose denizens to toxicological health implications [4][5][6][7][8][9].The ability of crude oil to cause these aberrations is predicated on the induction of free radicals [10]. Free radicals have been implicated in the peroxidation of lipids in all forms of life [11,12].…”

Section: Introductionmentioning

confidence: 99%

“…A good number of scientists who are in a bid to curtail the negative implications of ecotoxicological substances in animals have been testing a variety of plants and other organic products with antioxidant potentials [18][19][20][21][22][23][24][25][26][27]. It is on this basis that the protective potentials of many plants against crude oil toxicity are being examined [6,8,9].The emphasis of the current research is to determine the protective impact of Costus afer aqueous extract on crude oil-induced oxidative stress indicators in Wistar albino rats.…”

Section: Introductionmentioning

confidence: 99%

Protective influence of Costus afer Aqueous Extract In Rats Fed With Crude Oil Contaminated Diet as Measured by Employing Biochemical Indices

Mordi

Achuba

Ichipi-Ifukor

et al. 2021

eijs

Self Cite

View full text Add to dashboard Cite

The use of medicinal plants in the treatment of harmful impacts of xenobiotics in animals is attracting an increasing attention in recent times. The aim of the current study is to assess the preventive potential of Costus afer aqueous leaves extract (CAAE) in treating metabolic aberrations imposed by crude oil contaminated diet inWistar albino rats. Six groups of rats were treated as follows: A = Normal diet; B=Normal diet + 100 mg/kg body weight of CAAE; C =Normal diet + 200 mg/kg body weight of CAAE; D= Crude oil contaminated diet; E= crude oil contaminated diet + 100 mg/kg body weight of CAAE, F = crude oil contaminated diet + 200 mg/kg body weight of CAAE. After thirty days of exposure to the diet and administration of the corresponding plant extracts, the rats were sacrificed with chloroform and the required organs were excised. The hematological indices, as well as function indicators and levels of drug metabolizing enzymes in the liver and kidney, were investigated with standard protocols. The results indicated that the hematological parameters and kidney and liver function indices were altered in rats fed with crude oil contaminated diet. However, the values came close to those in control rats when Costus afer aqueous extracts were administered. Similarly, the activities of oxidase enzymes (aldehyde oxidase, monoamine oxidase, xanthine oxidase, and sulphite oxidase), following their inhibition by the ingestion of crude oil contaminated diet, equally restored close to control values upon treatment with Costus afer aqueous extract. This study, therefore, was able to establish an aqueous extract of Costus aferleave as an antidote for crude oil intoxication.

show abstract

Effect of Elaeis guineensis (Jacq) leaf extracts on crude oil-induced genotoxicity in Wistar albino rats

Cited by 6 publications

References 30 publications

Pretreatment with Oil Palm Leaf Extracts Confers Protection Against Crude Oil Adulterated Food (COAF)

Pretreatment with Oil Palm Leaf Extracts Confers Protection Against Crude Oil Adulterated Food (COAF)

Health risk assessment of polychlorinated biphenyls exposure from inland rivers sediments in Warri-South, Warri, Delta State

Protective influence of Costus afer Aqueous Extract In Rats Fed With Crude Oil Contaminated Diet as Measured by Employing Biochemical Indices

Contact Info

Product

Resources

About