2021
DOI: 10.3724/zdxbyxb-2021-0007
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Effect of electro-acupuncture therapy on limb spasm and excitability of motor neurons in stroke rats

Abstract: Objective: To investigate the effect of electro-acupuncture therapy on limb spasm and excitability of motor neurons in stroke rats. Methods: Ischemic stroke model was induced with middle cerebral artery embolization in SD rats. Thirty-three modeled rats were randomly divided into model group, electro-acupuncture group, and baclofen group with 11 rats in each group, and another 10 rats were taken as sham operation group.The electro-acupuncture group and the baclofen group were treated with electroacupuncture an… Show more

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Cited by 4 publications
(6 citation statements)
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“…Furthermore, it is reported that excitatory neurotransmitter and inhibitory neurotransmitter play an important role in the pathogenesis of spasticity ( Liu et al, 2021 ). In mouse model of middle cerebral artery occlusion (MCAO), the concentration of excitatory neurotransmitter Glutamate (Glu) increased in the ischemic area of cerebral hippocampus ( Qian et al, 2022 ).…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, it is reported that excitatory neurotransmitter and inhibitory neurotransmitter play an important role in the pathogenesis of spasticity ( Liu et al, 2021 ). In mouse model of middle cerebral artery occlusion (MCAO), the concentration of excitatory neurotransmitter Glutamate (Glu) increased in the ischemic area of cerebral hippocampus ( Qian et al, 2022 ).…”
Section: Discussionmentioning
confidence: 99%
“…(5) completeness of outcome data; (6) selective reporting of study results; (7) other biases. For each study, a judgment of "yes" (low risk of bias), "no" (high risk of bias), or "unclear" (lack of relevant information or uncertainty about bias) was made for each item.…”
Section: Risk Of Bias and Quality Assessmentmentioning
confidence: 99%
“…Studies have shown that acupuncture can improve cerebral blood supply, promote neuron recovery, and thus alleviate limb spasms. [6,7] A meta-analysis of randomized controlled trials (RCTs) comparing acupuncture to sham acupuncture or standard treatment showed that acupuncture is effective in improving scores on the modified Ashworth spasticity assessment scale (MAS). [8] Scalp acupuncture (SA) is a type of acupuncture technique that combines traditional Chinese meridian theory with modern cortical functional localization, offering greater therapeutic effects in treating cerebral diseases.…”
Section: Introductionmentioning
confidence: 99%
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“…Mao et al [ 13 ] report that lncRNA KLF3-AS1 in MSC-Exos attenuates myocardial infarction by inhibiting pyroptosis in cardiomyocytes [ 13 ]. Li et al [ 49 ] observe that lncRNA histocompatibility leukocyte antigen complex P5 (HCP5) in BMSC-Exos protects cardiomyocytes against ischemia/reperfusion (IR) injury [ 14 ]. However, the lncRNAs involved in the action mechanisms of BMSC-Exos in HF have rarely been reported.…”
Section: Introductionmentioning
confidence: 99%