Effect of elevated iron intake on the copper status of grazing cattle

Campbell, A. G.; Coup, M. R.; Bishop, W.H.; Wright, D. E.

doi:10.1080/00288233.1974.10421023

Cited by 50 publications

(21 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As soils differ in their chemical and physical properties, different soils could be expected to have different influences on the mineral status of the grazing animal. For instance, studies have shown that soil ingestion may raise or lower the Cu status of livestock (Campbell et al 1974;Suttle et al 1975;Mayland et al 1977;Langlands et al 1982;Grace et al 1996). In southern Australia, the seasonal incidence of Co deficiency in livestock is thought to be due to the dilution of Co in rapidly growing spring pasture and to the ingestion of soil Co on dry autumn pastures or on short winter pastures.…”

Section: Soil Contamination and Ingestionmentioning

confidence: 99%

Mineral disorders in grazing livestock and the usefulness of soil and plant analysis in the assessment of these disorders

Judson¹,

McFarlane²

1998

Aust. J. Exp. Agric.

View full text Add to dashboard Cite

Summary. This paper briefly describes common mineral disorders affecting livestock at pasture in Australia, their mineral requirements, factors affecting these requirements and laboratory methods of assessing the mineral status of the animal. The benefits and limitations of mineral analyses of soil and pasture samples for the purposes of identifying and preventing mineral disorders of the grazing animal are discussed. Mineral analyses of pasture are of particular value in the identification of the causes of copper and magnesium deficiency and of acute calcium deficiency in livestock. Selective grazing, adventitious ingestion of soil and variability in the mineral reserves of the animal, however, limit the usefulness of pasture analyses to identify a mineral disorder in the grazing animal.

show abstract

Section: Soil Contamination and Ingestionmentioning

confidence: 99%

Mineral disorders in grazing livestock and the usefulness of soil and plant analysis in the assessment of these disorders

Judson¹,

McFarlane²

1998

Aust. J. Exp. Agric.

View full text Add to dashboard Cite

show abstract

“…Iron concentrations in forages vary greatly (Underwood, 1977). Although there is little convincing evidence that dietary Fe deficiency ever occurs in ruminants grazing pasture (Underwood, 1977), ruminants grazing pasture or being fed harvested silage or hay frequently may be exposed to excessive levels of Fe through forage, water or soil ingestion (Coup and Campbell, 1964;Campbell et al, 1974;Humphries et al, 1983). Excess dietary Fe can affect performance adversely in ruminants (Coup and Campbell, 1964;Standish et al, 1969;Koong et al, 1970;.…”

Section: Introductionmentioning

confidence: 99%

“…Excess dietary Fe can affect performance adversely in ruminants (Coup and Campbell, 1964;Standish et al, 1969;Koong et al, 1970;. High dietary Fe can affect utilization of other minerals such as Cu, P, Zn and Mn (Standish et al, 1969Campbell et al, 1974;Humphries et al, 1983). Studies evaluating high dietary Fe have been conducted with concentrate-based diets; however, detrimental effects of excessive Fe intake are most likely to occur in ruminants consuming forages.…”

Section: Introductionmentioning

confidence: 99%

Effects of Dietary Iron on Performance and Mineral Utilization in Lambs Fed a Forage-Based Diet

Prabowo

Spears

Goode

1988

Journal of Animal Science

View full text Add to dashboard Cite

Twenty-four lambs, averaging 29 kg, were used to determine the effect of supplemental dietary Fe on performance and Cu, P, Zn and Mn utilization. Treatments consisted of supplemental Fe at 0, 300, 600 or 1,200 mg/kg diet as ferrous carbonate. The basal diet contained 154 mg Fe/kg diet and consisted of 90% Coastal bermudagrass pellets, 9.45% group corn, .5% sodium chloride and .05% vitamin mix. Lambs were slaughtered after having ad libitum access to diets for 98 to 121 d. Dietary Fe did not affect lamb gain or feed intake. Supplemental Fe increased Fe concentrations in liver (P less than .01), spleen (P less than .01) and bone (P less than .10), but not in kidney and muscle. Serum Fe concentrations and percentage transferrin saturation in serum were increased (P less than .01) by supplemental Fe at 28 and 84 d, but not at the termination of the study. Plasma Cu was decreased (P less than .01) at 56 d, whereas serum ceruloplasmin activity was reduced (P less than .01) at 28 d in lambs fed 1,200 mg Fe/kg diet compared with lambs fed 600 mg Fe/kg diet. Lower levels of Fe (300 and 600) reduced (P less than .01) ceruloplasmin by 56 d and plasma Cu by 84 d compared with controls. Liver Cu also was decreased (P less than .05) by supplemental Fe. Plasma P was decreased slightly (P less than .10) by 28 d and significantly (P less than .01) at the other sampling dates by supplemental Fe.(ABSTRACT TRUNCATED AT 250 WORDS)

show abstract

“…Bremner et al, 1987). Iron is known to be an important antagonist to copper (Standish et al, 1969;Standish and Ammerman, 1971;Campbell et al, 1974;Prince et al, 1979), but also to zinc and manganese (Grün et al 1978). However, considering the high dietary exposure of cattle to iron, e.g.…”

Section: Safety Of Iron For Animal Speciesmentioning

confidence: 99%

Scientific Opinion on the safety and efficacy of iron compounds (E1) as feed additives for all species: Ferrous sulphate monohydrate based on a dossier submitted by Kronos International, Inc.

2014

EFS2

View full text Add to dashboard Cite

Ferrous sulphate monohydrate is safe when supplied up to a maximum iron content per kilogram complete feedingstuff of 450 mg for bovines and poultry, 500 mg for ovines, 600 mg for pets, and 750 mg for other species/categories, except horses and fish; for piglets up to one week before weaning a maximum of 250 mg Fe/day is considered safe. Because of insufficient data on horses and fish, as a provisional measure, the current value (750 mg Fe/kg) could be maintained. The values for total dietary iron for pigs, ovines, horses, fish and other species/categories (except poultry, bovines and pets) are in line with those currently authorised. Iron from ferrous sulphate monohydrate is unlikely to modify the iron concentration in edible tissues and products of animal origin. Consumer exposure in the EU is not associated with a risk of excess iron intake to the general population. Therefore, the FEEDAP Panel does not foresee any concern for consumer safety resulting from the use of ferrous sulphate monohydrate in animal nutrition, provided that the maximum iron content in complete feedingstuffs is respected. Ferrous sulphate monohydrate is irritant and corrosive to the skin, eyes and respiratory tract. The additive contains up to 109 mg Ni/kg. Nickel is a dermal and respiratory sensitiser, and inhalation may cause lung cancer. Thus, handling the additive poses a risk to the user/worker. Considering the high concentration of iron and sulphur in soil and water, the supplementation of feed with the additive is not expected to pose an environmental risk. Ferrous sulphate monohydrate is an effective iron source for all animal species and categories. The FEEDAP Panel recommends that the currently authorised maximum iron content in complete feed be reduced for bovines and poultry from 750 to 450 mg Fe/kg, and for pets from 1250 to 600 mg Fe/kg.

show abstract

Effect of elevated iron intake on the copper status of grazing cattle

Cited by 50 publications

References 15 publications

Mineral disorders in grazing livestock and the usefulness of soil and plant analysis in the assessment of these disorders

Mineral disorders in grazing livestock and the usefulness of soil and plant analysis in the assessment of these disorders

Effects of Dietary Iron on Performance and Mineral Utilization in Lambs Fed a Forage-Based Diet

Scientific Opinion on the safety and efficacy of iron compounds (E1) as feed additives for all species: Ferrous sulphate monohydrate based on a dossier submitted by Kronos International, Inc.

Contact Info

Product

Resources

About