Abstract:Background: Anxiety is one the most common psychiatric disorders. Recently, anti-oxidants have been shown to possess anxiolytic properties. Objectives: The present study aimed to investigate anxiolytic effect of ellagic acid (EA) in mice and its interaction with GABAA receptor. Materials and Methods: 184 male albino mice (25 -30 g) were randomly assigned into two subgroups (12 groups in each). In the first set of experiments, to evaluate acute administration of EA (single dose) on anxiety, experimental groups … Show more
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