Effect of essential oils from Mangifera indica L. cultivars on the antifungal susceptibility of Candida spp. strains isolated from dogs

Abstract

SUMMARY This work reports the chemical study, and anti-Candida spp. activity of leaf essential oil from Mangifera indica cultivars. The essential oils were obtained by hydro-distillation and analyzed by gas chromatography/mass spectroscopy. The anti-Candida spp. activity was evaluated against strains isolated from dogs by the agar-well diffusion method and the minimum inhibitory concentration (MIC) by the broth microdilution method. Tommy Atkins cultivar presented β–selinene (29.49%), caryophyllene oxide (12.40%) and humulene II epoxide (8.66%) as main constituents, while the main constituents of Rosa, Moscatel and Jasmim varieties were caryophyllene oxide (23.62, 48.42 and 30.77%, respectively) and humulene epoxide II (11.56, 23.45, and16.27%, respectively). The means of inhibition zones were 11 ± 0.71, 13.5 ± 3.54, 10.5 ± 0.71 and 13.5 ± 0.71mm to Tommy Atkins, Rosa, Moscatel and Jasmim varieties, respectively. For Tommy Atkins, the MIC ranged from 0.62 to 1.25 mg/mL; for Rosa, ranged from 0.31 to 1.25 mg/mL; for Jasmim ranged from 0.31 to 0.62 mg/mL; while for the Moscatel variety the MIC value was 1.25 mg/mL for all Candida strains. Essential oils of four M. indica cultivars were active in vitro against Candida spp., demonstrating good antifungal activity and can be a useful source of antifungal compounds for veterinary medicine.

Mango (Mangifera indica L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities

“…Other constituents that were common in all the four varieties were spathulenol, italicene epoxide, caryphyllene oxide, cyclocolorenone, and humulene epoxide II. This study also reported sesquiterpenoids as the major compound of MLO [ 17 ]. The essential oil from MLs also possesses bacteriostatic properties and contains several antimicrobial constituents such as gurjunene, trans-caryophyllene, humulene, selinene, and camphor.…”

Effect of the essential oil from the latex of the fruit Mangifera indica L. on Tetranychus urticae Koch (Acari, Tetranychidae)

“…Depending on how the harvesting is performed, this latex can "burn" the peel, which depreciates the commercial value of the fruit (Robinson et al, 1993). A recent investigation addressing the biological properties of the essential oil from the latex of mango has revealed antimicrobial (Fontenelle et al, 2017), antifungal (Perumal et al, 2017), leishmanicidal and cytotoxic (Ramos et al, 2014) properties. However, no studies have investigated the acaricidal potential or the effects on the behavior of Tetranychus urticae Koch (Acari: Tetranychidae).…”

Caracterización química y actividad antibacteriana del aceite esencial de Mangifera indica L. de tres regiones de Venezuela

“…De la variedad Corazao de boi se hallaron: cipereno (32,62%), (E)-cariofileno (26,91%), α-humuleno (17,12%), terpinoleno (2,32%), β-selineno (5,70%) y mirceno (2,80%). En el mismo año, Fontanelle et al [21] señalaron, como constituyentes principales, para la variedad Tommy-Atkins los siguientes compuestos: β-selineno (29,49%), óxido de cariofileno (12,40%) y epóxido II de humuleno (8,66%); y para las variedades Rosa, Moscatel y Jazmín: óxido de cariofileno (23,62, 48,42 y 30,77%, respectivamente) y epóxido II de humuleno (11,56, 23,45 y 16,27%, respectivamente). Por otra parte, Gebara et al [22] también reportaron altas proporciones de estos compuestos en el aceite esencial obtenido de las hojas de la variedad Coquinho.…”