1996
DOI: 10.1016/s0378-5122(96)01063-8
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Effect of estrogen replacement therapy on natural killer cell activity in postmenopausal women

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Cited by 30 publications
(23 citation statements)
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“…Previous reports have indicated that the NK cell activity declined with ageing and was associated with the female immune system. 26,27) These facts suggest that the level of estrogen could be strongly connected with the regulation of NK/NKT cell activity.…”
Section: Discussionmentioning
confidence: 95%
“…Previous reports have indicated that the NK cell activity declined with ageing and was associated with the female immune system. 26,27) These facts suggest that the level of estrogen could be strongly connected with the regulation of NK/NKT cell activity.…”
Section: Discussionmentioning
confidence: 95%
“…Greater muscle mass, testosterone and GH levels and the lesser propensity to dysregulation of the hypothalamicadrenal axis and cortisol secretion may protect males from physical decline (15)(16)(17)(18)(19). A distinctive age-related change in the immune system probably makes men more vulnerable to infections and less prone to chronic conditions which are ultimately responsible for muscle loss (20,21). Lastly, earlier mortality may eliminate men at greater risk of developing functional impairment (22).…”
Section: Discussionmentioning
confidence: 99%
“…Because not all CD16+ cells were double labeled for CD14 another source of CD16+ cells could be migration of natural killer cells or granulocytes, which also express CD16, into the inflamed TMJ region from the circulatory system. Although, estrogen has been shown to have no effect on antibody-dependent cytotoxicity in natural killer cells [49].…”
Section: Discussionmentioning
confidence: 99%