In a prospective study of 14 patients undergoing total hip replacement we have used dual-energy X-ray absorptiometry (DEXA) to investigate remodelling of the bone around two different designs of cementless femoral prosthesis. The bone mineral density (BMD) was measured at 12-weekly intervals for a year. Eight patients (group A) had a stiff, collarless implant and six (group B) a flexible isoelastic implant.Patients in group A showed a decrease in BMD from 14 weeks after operation. By 12 months, the mean loss in BMD was 27%, both medially and laterally to the proximal part of the implant. Those in group B showed an overall increase in BMD which reached a mean of 12.6% on the lateral side of the distal portion of the implant.Our results support the current concepts of the effects of stem stiffness and flexibility on periprosthetic remodelling. [Br] 1997;79-B:675-9. Received 14 November 1996; Accepted after revision 11 March 1997 Periprosthetic bone remodelling after total hip replacement (THR) has been the subject of much research and debate. Most occurs within three years and it is progressive. Dualenergy X-ray absorptiometry (DEXA) has been shown to be an accurate and reproducible method of measuring periprosthetic bone remodelling and with this technique changes may be seen as early as six months after operation.
J Bone Joint Surg