2005
DOI: 10.4103/0019-5359.13905
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Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats

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Cited by 98 publications
(59 citation statements)
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“…Treatment of diabetic rats with different spice extracts has been reported to reverse degeneration of the pancreas (Jelodar et al 2005;Abdollahi et al 2011).…”
Section: Histopathological Evaluationmentioning
confidence: 99%
“…Treatment of diabetic rats with different spice extracts has been reported to reverse degeneration of the pancreas (Jelodar et al 2005;Abdollahi et al 2011).…”
Section: Histopathological Evaluationmentioning
confidence: 99%
“…Citrullus colocynthis (Cucurbitaceae) (C. colocynthis), commonly known as "bitter apple", "colosynth", "vine-of-sodom" and "tumba" is a well-known fruit traditionally used as an antidiabetic medication in the Mediterranean countries [6] . The ingredients of this plant may act on blood glucose through different mechanisms; some of them may have insulin's activity [7] . Oxidative stress plays an important role in the chronic complications of diabetes mellitus.…”
Section: Introductionmentioning
confidence: 99%
“…Such mechanisms include promoting biosynthesis of enzymes and structural molecules required for regeneration and restoration of the functional integrity of insulin secreting cells (Islet of Langerhans) in concert with quick acting mechanism of insulin mimicking. [40,[69][70] The leaves of Gymnema sylvestre (Gumer) [71] and the fruits of T. catappa Linn [50] induced β-cell regeneration in simultaneous with β-cell stimulation and suppression of gluconeogenic enzymes [72] that corroborates the plausible mode of action of V. amygdalina, A. indica and M. oleifera extracts. From another perspective, Ugochukwu and Babady, [73] reported that the long-term hypoglycemic property of Gongronema latifolium extract was mediated by activation of hepatic hexokinase, phosphofructokinase, glucose-6-phosphate dehydrogenase in diabetic rats.…”
Section: Discussionmentioning
confidence: 53%