The present study assessed the effect of common hop (Humulus lupulus L.) extract on common carp (Cyprinus carpio L.). Fish (initial weight of 32.22 ± 0.65 g) were divided into three groups and fed diets containing 0 (control), 0.75 g (H0.75), and 1.5 g (H1.5) of common hop extract per kg of isonitrogenous, isolipidic, and isoenergetic commercial diet for 8 weeks. No significant differences in growth performance across treatments were observed (p > 0.05). Protein content in whole‐body proximate composition increased significantly in H1.5 compared to the control (p < 0.05). The H0.75 showed a significant increase in lipid peroxidation (LPO) and reduced glutathione (GSH) levels compared to the control (p < 0.05). While H1.5 had higher acetylcholinesterase (AChE) than group H0.75 (p < 0.05), no significant change was observed in AChE, catalase (CAT), and superoxide dismutase (SOD) activities in treated groups compared to the control (p > 0.05). Blood biochemical indices, alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were significantly lower in H0.75 and H1.5 than in the control (p < 0.05), while lactate dehydrogenase (LDH) increased significantly in H1.5 compared to the control (p < 0.05). Cholesterol, triglyceride (TG), and the number of white blood cells (WBCs) showed no significant differences across treatments (p > 0.05). H0.75 significantly increased the proportion of polyunsaturated fatty acids (PUFAs) like α‐linolenic acid, docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA; p < 0.05), and both H0.75 and H1.5 raised considerably the value of oleic acid and eicosatrienoic acid compared with the control (p < 0.05); in contrast, eicosapentaenoic acid (EPA) was decreased significantly by H1.5 compared to the control (p < 0.05). Supplementation of the common hop at 0.75 and 1.5 g kg−1 positively affected farmed carp.