Effect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia

Portela, Gerard T.; Carson, Jeffrey L.; Swanson, Sonja A.; Alexander, John H.; Hébert, Paul C.; Goodman, Shaun G.; Steg, Philippe Gabriel; Bertolet, Marnie; Strom, Jordan B.; Fergusson, Dean A.; Simon, Tabassome; White, Harvey D.; Cooper, Howard A.; Abbott, J. Dawn; Rao, Sunil V.; Chaitman, Bernard R.; Fordyce, Christopher B.; Lopes, Renato D.; Daneault, Benoit; Brooks, Maria M.; ,; Salisbury, Adam C.; Gershon, Adam; Adeboye, Adedayo; Carbonaro, Adriana; Caixeta, Adriano; Rene, Aglae Garvey; Lee, Agnes; Mizyed, Ahmad; Hassanin, Ahmed; Kone, Aichetou; Cherian, Ajini; Bagai, Akshay; Gulliver, Alana; Easton, Aleisha; Rousseau, Alexandra; Gautier, Alexandre; Quadros, Alexandre; Dantigny, Alexia; Ep, Alexia; Ghamraoui, Ali; Jacobs, Alice; Giacomo, Aline; Schley, Allison; Barnett, Amanda; Bollino, Amanda; Logan, Amanda; Salvatore, Amanda; Tice, Amanda; Grelier, Amandine; Ruissel, Amandine; Patel, Ameen; Patel, Ami; Zamiti-Smondel, Amina; McMeans, Amy; Sarafolean, Andrea; Baker, Andrew; Goldsweig, Andrew M.; DeFilippis, Andrew P.; Starovoytov, Andrew; Camilo, Angeline; Andrieu, Angélique; Adler, Angie; Pham, Anh-Phuong; Centurione, Anna Helena Felipe Pereira; Koulova, Anna; Law, Anna; Tran, Anna; Druart, Anne; Fayol, Antoine; Lequipar, Antoine; Tirumani, Anuritha; 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doi:10.7326/m24-0571

Ann Intern Med

2024

DOI: 10.7326/m24-0571

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Effect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia

Gerard T. Portela,

Jeffrey L. Carson,

Sonja A. Swanson

et al.

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2024

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Cited by 3 publications

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Do patients with acute myocardial ischemia need to be transfused with a higher hemoglobin threshold?

Hébert,

Carson

2024

Canadian Journal of Cardiology

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Do patients with acute myocardial ischemia need to be transfused with a higher hemoglobin threshold?

Hébert,

Carson

2024

Canadian Journal of Cardiology

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Preventing, identifying and managing myocardial injury after non cardiac surgery – a narrative review

Wittmann,

Dinc,

Kunsorg

et al. 2024

Current Opinion in Anaesthesiology

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Purpose of review There is mounting and convincing evidence that patients with postoperative troponin elevation, with or without any clinical symptoms, are at higher risk for both, short- and long-term morbidity and mortality. Myocardial injury after noncardiac surgery (MINS) is a relatively newly described syndrome, and the pathogenesis is not fully understood yet. MINS is now an established syndrome and multiple guidelines address potential etiologies, triggers, as well as preventive and management strategies. Recent findings Surveillance in high-risk patients is required, as most MINS would otherwise be missed. There is no reliable and established preventive strategy, but several potentially avoidable triggers like hypotension, pain and anemia have been identified. Managing patients with MINS postoperatively includes minimizing triggers (such as hemodynamic abnormalities and anemia) that can continue the damage. Long-term pharmacologic strategies include beta-blockers, statins, antiplatelet agents, and anticoagulation. Summary MINS affects up to 20% of surgical patients, remains clinically mostly silent, but is associated with elevated morbidity and mortality. A multidisciplinary approach, that includes involvement of anesthesiologists, for the prevention, diagnosis, and treatment of MINS is recommended.

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Relaxing Transfusion Thresholds for Patients With Myocardial Infarction: Findings From the MINT Trial

Bloch,

Tobian

2024

Ann Intern Med

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Effect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia

Cited by 3 publications

References 43 publications

Do patients with acute myocardial ischemia need to be transfused with a higher hemoglobin threshold?

Do patients with acute myocardial ischemia need to be transfused with a higher hemoglobin threshold?

Preventing, identifying and managing myocardial injury after non cardiac surgery – a narrative review

Relaxing Transfusion Thresholds for Patients With Myocardial Infarction: Findings From the MINT Trial

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