Effect of genetic strains (Ross 308, Cobb 500 and Hubbard F15) on immune response against Newcastle disease vaccine in broiler chickens

Abstract

Genetic Strains The current study examines immune response against Newcastle disease vaccine in Ross 308, Cobb 500, and Hubbard F15 strains. Newcastle Disease Newcastle disease virus (NDV) is a variant of avian Abstract Background: Immune responses are crucial for optimal health and can be affected by several factors including host genetics. Genetic selection would seem to have some effects on immunological memory. Some genes control disease resistance in broiler chickens. Noticeable increase in the production potential of broiler chickens has been observed recently. One way to increase the production potential of commercial broiler chickens is utilization of genetic selection. Genetic enhancements in growth rate and carcass weight reported in new broiler lines, and these new lines have shorter breeding period. High growth rate in broiler chickens has some negative consequences. Fast-growing birds as compared to slower-growing birds, have high mortality, because high growth rate may lead to metabolic diseases or infections. Objectives: The current study examines immune response against Newcastle disease vaccine in Ross 308, Cobb 500, and Hubbard F15 strains. Materials and Methods: A total of 36 000 one-day-old broiler chicks of Hubbard F15, Cobb 500, and Ross 308 strains were divided into 3 equal groups with 2 replicates and 6000 birds per replicate. The birds were reared under similar conditions from 1-day-old to 49 days of age. All groups were vaccinated against Newcastle disease. Blood samples were collected before vaccination and on 7, 17, 27, 35, 42, 48 days of age and antibody titer against Newcastle disease vaccine was determined by Hemagglutination inhibition (HI) test. Results: The Cobb 500 and Hubbard F15 stains, respectively, had the highest and the lowest immune responses against Newcastle disease vaccine. Ross 308 had the second status among the strains. Conclusion: On the basis of present study, Cobb 500 and Ross 308 chickens had better immune responses against Newcastle disease vaccine and therefore are recommended for rearing, respectively.

The ability to resist Newcastle disease through inherited immunity in different strains of broilers in Nineveh governorate

“…The VI seems to be a logical parameter to compare the serological response between Cobb 500 and Ross 308 strains in their maternal antibody titer transmitted to their off-springs, as VI gives a high score with a good vaccination (high mean titer, low percentage CV) in Cobb 500 strain, and a lower score with a less titer after vaccination (low mean titer, high percentage CV) in Ross 308 strain. The effect of broiler strain on the immune response was also reported by Mayahi et al (2016) , who showed that Cobb 500 had the highest immune responses against ND vaccine than Ross 308, which was in the second order.…”

“…Both hybrids Cobb 500 and Ross 308 are excellent to keep by following the housing and feeding requirements ( Strakova et al , 2015 ). They achieve weights of 2 kg and above in 42 days, but the superior genetics of Cobb 500 give an extra edge to this hybrid breed, since, Cobb 500 has better average daily weight gains and growth performance ( El-Tahawy et al , 2017 ; Pascalau et al , 2017 ) and better immune defense system to counter diseases than Ross 308 ( Mayahi et al , 2016 ; Gholami et al , 2020 ). Immune responses are crucial for optimal health and affected by host genetics.…”

Alterations in bacterial metabolites, cytokines, and mucosal integrity in the caecum of broilers caused by feed additives and host-related factors

“…There are also some evidences showing that broiler’s intestinal microbiota can be affected by host genotype ( Emami et al, 2022 ) and sex ( Lumpkins et al, 2008 ). Despite the fact that commercial broilers are co-selected for performance and immunocompetence, their genetic make-up still affects their immune response to certain challenges ( Cheema et al, 2003 ; Mayahi et al, 2016 ). For instance, different immunological developments and inflammatory responses (e.g.…”