Effect of Ginkgo Leaf Parenteral Solution on Blood and Cochlea Antioxidant and Immunity Indexes in OM Rats

Zhao, Jiandong; Su, Yu Ting; Chen, Aiting; Hu, Yuan; Liu, Liangfa; Wu, Wenyue

doi:10.3390/molecules161210433

Cited by 10 publications

(7 citation statements)

References 46 publications

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“…In this study, rams in G60 and G100 groups had a considerably higher IgA, IgG and IgM values compared to those in the G0 group, which might due to the phenolic compounds and flavonoids in the bark and leaves of B. papyrifera, which apparently are the main components responsible for the antioxidant activity (Du et al 2008;Kai et al 2015). Previous studies have shown that plant flavonoids are a predominant class of plant secondary metabolites with immunity-boosting activities (Middleton 1998;Proestos et al 2006;Zhao et al 2011), they can extend the activity of vitamin C, act as antioxidants, and may, therefore, enhance immune functions (Acamovic and Brooker 2005). Si et al (2018) also observed an increase in IgA, IgG and IgM in the serum of dairy cows with the addition of B. papyrifera silage (Si et al 2018).…”

Section: Discussionmentioning

confidence: 92%

Effect of Broussonetia papyrifera L. (paper mulberry) on growth performance, carcase traits, meat quality and immune performance in Hu ram lambs

Sheng

et al. 2021

Italian Journal of Animal Science

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This study was carried out in an attempt to evaluate the impact of Broussonetia papyrifera as a roughage substitute at different levels on carcase traits, growth performance, meat quality and immune performance in Hu ram lambs. Sixty Hu rams (5 months of age, 26.70 ± 2.14 kg body weight) were randomly divided into four groups. The treatments comprised B. papyrifera supplementation at levels of 0% (G0), 30% (G30), 60% (G60) and 100% (G100) of roughage feed. The results suggested that diet supplemented with B. papyrifera (G100 group) caused a higher average weight gain (AWG) and average daily gain (ADG) than those of G0 group. The highest carcase weight was observed in the G60 group. The chemical and physical properties of the longissimus dorsi muscle of Hu rams showed no significant differences (p>.05). For fatty acid, the G60 group had significantly lower content of saturated fatty acids (SFAs), higher contents of monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs) and higher PUFA/ SFA ratio than other groups (p<.05). In terms of the immune response, G60 and G100 groups significantly showed a significant rise in the immunoglobulins (IgG, IgA and IgM) (p<.05). This study indicated multiple beneficial effects of the inclusion of B. papyrifera (60% of the roughage feed) on the growth performance, carcase traits, meat quality and immune response in Hu rams. It could be used as a high-quality unconventional feedstuff for rams. HIGHLIGHTSThe addition of Broussonetia papyrifera to the diet resulted in a significant improvement in the average weight gain (AWG) and average daily gain (ADG) of Hu rams. Adding appropriate proportion of B. papyrifera in diets positively modulates fatty acid percentage in the longissimus dorsi muscle, and also increases immunoglobulins (IgG, IgA and IgM) in blood. Broussonetia papyrifera could be used as a high-quality unconventional feedstuff for rams and has a positive effect on their growth performance, meat quality and immune performance.

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Section: Discussionmentioning

confidence: 92%

Effect of Broussonetia papyrifera L. (paper mulberry) on growth performance, carcase traits, meat quality and immune performance in Hu ram lambs

Sheng

et al. 2021

Italian Journal of Animal Science

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“…Biological systems have protective arrangements which defend them against the harmful effects of free radicals. This includes SOD and CAT [22]. In the liver tissues of the hepatotoxicity control group, the antioxidant activity of SOD and CAT were significantly ( p < 0.001) reduced as compared with the normal animal group.…”

Section: Resultsmentioning

confidence: 99%

Ipomoea aquatica Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity

et al. 2012

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Abstract:In the Indian system of traditional medicine (Ayurveda) it is recommended to consume Ipomoea aquatica to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of I. aquatica against liver damage were evaluated in thioacetamide (TAA)-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD) rats were orally fed with I. aquatica (250 and 500 mg/kg) for two months along with administration of TAA (i.p injection 200 mg/kg three times a week for two months). The results showed that the treatment of I. aquatica significantly lowered the TAA-induced serum levels of hepatic enzyme markers (ALP, ALT, AST, protein, albumin, bilirubin and prothrombin time). The hepatic content of activities and expressions SOD and CAT that were reduced by TAA were brought back to control levels by the plant extract supplement. Meanwhile, the rise in MDA level in the TAA receiving groups also were significantly reduced by I. aquatica treatment. Histopathology of hepatic tissues by H&E and Masson trichrome stains displayed that I. aquatica has reduced the incidence of liver lesions, including hepatic cells cloudy swelling, infiltration, hepatic necrosis, and fibrous connective tissue proliferation induced by TAA in rats. Therefore, the results of this study show that the protective effect of I. aquatica in TAA-induced liver damage might be contributed to its modulation on detoxification enzymes and its antioxidant and free radical OPEN ACCESSMolecules 2012, 17 6147 scavenger effects. Moreover, it confirms a scientific basis for the traditional use of I. aquatica for the treatment of liver disorders.

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“…It is well documented that the active compounds of flavones and terpenes in GBL have immune enhancing activities that include promotion of lymphocyte synthesis, cytokine release, immunoglobulin levels and phagocytosis activity (Zhao et al . ). In the present study, diets supplemented with FGBLR enhanced both humoral and cellular immunity of piglets.…”

Section: Discussionmentioning

confidence: 97%

Effects of dietary supplementation of fermented Ginkgo biloba L. residues on growth performance, nutrient digestibility, serum biochemical parameters and immune function in weaned piglets

Zhou

Wang

et al. 2015

Animal Science Journal

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This study evaluated the effects of fermented Ginkgo biloba L. residues (FGBLR) on growth performance, nutrient digestibility, serum biochemical parameters and immune function in weaned piglets. Pigs were allotted to five dietary treatments, including negative control (NC: antibiotic free basal diet), positive control (PC) (NC + 30 mg apramycin/kg) and FGBLR-50, 100, 150 (NC + 50, 100, 150 g FGBLR/kg). Pigs in FGBLR-100 and PC treatments showed increased final body weight, average daily gain, gain:feed and apparent total tract digestibility of dry matter, N and gross energy (P < 0.05) compared with NC, FGBLR-50 and FGBLR-150 treatments, In addition, pigs fed with FGBLR-100 diet showed higher serum total protein, albumin, alkaline phosphatase, glucose, hemoglobin, total iron, total iron binding capacity, superoxide dismutase and glutathione superoxide dismutase levels, and lower serum blood urea nitrogen, malondialdehyde, glutamic-pyruvic transaminase, glutamic-oxalacetic transaminase, triglyceride and total cholesterol levels than those fed with PC and NC diets (P < 0.05). Moreover, feeding FGBLR-100 could increase levels of immunoglobulin G (IgG), IgA and IgM, as well as lymphocyte transformation rates, ratio of CD4+ to CD8+ cells and proportions of CD2+, CD4+, B, major histocompatibility complex (MHC)-I and MHC-II cells, and can decrease proportion of CD8+ cells in blood of piglets compared with PC and NC groups (P < 0.05). These results indicate that dietary supplementation with 10% of FGBLR showed greatest beneficial effects on growth performance, nutrient digestibility, serum biochemical parameters and immune function in weaned piglets, which were superior to antibiotic supplemental diets.

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Effect of Ginkgo Leaf Parenteral Solution on Blood and Cochlea Antioxidant and Immunity Indexes in OM Rats

Cited by 10 publications

References 46 publications

Effect of Broussonetia papyrifera L. (paper mulberry) on growth performance, carcase traits, meat quality and immune performance in Hu ram lambs

Effect of Broussonetia papyrifera L. (paper mulberry) on growth performance, carcase traits, meat quality and immune performance in Hu ram lambs

Ipomoea aquatica Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity

Effects of dietary supplementation of fermented Ginkgo biloba L. residues on growth performance, nutrient digestibility, serum biochemical parameters and immune function in weaned piglets

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