Effect of Gluten-Free Diet on Pregnancy Outcome in Celiac Disease Patients with Recurrent Miscarriages

Tursi, Antonio; Giorgetti, GianMarco; Brandimarte, Giovanni; Elisei, Walter

doi:10.1007/s10620-008-0242-x

Cited by 36 publications

(20 citation statements)

References 23 publications

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“…A correlation between maternal coeliac disease and recurrent miscarriage has been shown53; patients with proven coeliac disease should already be on a gluten-free diet 54. Thus, screening for antibody to transglutaminase IgA isotype in the recurrent miscarriage population could be warranted.…”

Section: Aetiology Of and Risk Factors For Recurrent Miscarriagementioning

confidence: 99%

Recurrent miscarriage: causes, evaluation and management

Garrido¹,

Alijotas‐Reig

2015

Postgraduate Medical Journal

214

135

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Recurrent miscarriage is frustrating for the physician and a heartbreaking experience for the patient. Approximately 5% of couples trying to conceive have two consecutive miscarriages. Despite a thorough study of patients, the aetiology of this common obstetric complication is unknown in 50% of cases. Known causes include abnormal chromosomes, endocrinological disorders and uterine abnormalities. Although antiphospholipid antibodies have been demonstrated in miscarriages, the role played by alloimmune mechanisms remains unclear. New immunological approaches such as natural killer cells, regulatory T cells, tumour necrosis factor α, cell-derived microparticles, leptin, certain glycoproteins and cytokines should be considered. The management of thyroid diseases and immunological disorders is continuously evolving. Several genetic diagnostic procedures such as parental karyotyping and preimplantation genetic screening should probably not be used routinely. Antiphopholipid syndrome and some recurrent miscarriage-related endocrinological disorders can be effectively treated. Finally, new therapeutic approaches and the pleiotropic effects of old ones have led to improved fetal-maternal outcomes.

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Section: Aetiology Of and Risk Factors For Recurrent Miscarriagementioning

confidence: 99%

Recurrent miscarriage: causes, evaluation and management

Garrido¹,

Alijotas‐Reig

2015

Postgraduate Medical Journal

214

135

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“…In the different studies, factors that help to measure fertility were measured, such as the anti-Müllerian hormone, since we speak of middle-aged adult women [39]. They also used routine physical examinations such as weight [5,7,10,20,26,27,32,51], height [5,7,10,20,26,27,32,51], body mass index (BMI, a formula that uses weight and height) [5,7,10,20,26,27,32,51], fat mass, and energy consumption [4,5], which were compared with their clinical analysis to be able to complement the patient's profile and to make a diagnosis. Analysis of the food consumed can also be found in order to help the patient with his or her nutritional treatment, which is the only known treatment for CD [5].…”

Section: Characteristic Of the Included Studiesmentioning

confidence: 99%

Tools Used to Measure the Physical State of Women with Celiac Disease: A Review with a Systematic Approach

Martínez-Rodríguez

Loaiza-Martínez

Sánchez-Sánchez

et al. 2020

IJERPH

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Celiac disease (CD) is an immunological disorder that mainly affects the small intestine, generating an inflammatory process in response to the presence of gluten (a protein). Autoimmune diseases are part of a group of diseases that are difficult to diagnose without a specific protocol or consensus to detect them due to the number of symptoms and diseases with which it has a relationship. Therefore, the aim of this review was to analyze the diagnostic tools of CD used in middle-aged women, to compare the use and effectiveness of the different tools, and to propose a strategy for the use of the tools based on the results found in the literature. The present research followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. The search was conducted in the following databases: Scielo, PubMed, Web of Science, and Worldwide Science org. In the initial literature search, 2004 titles and relevant abstracts were found. Among them, 687 were duplicates, leaving 1130 articles. Based on the inclusion criteria, only 41 articles passed the selection process; 4 main types of analyses appear in the studies: blood tests, questionnaires, clinical history, and biopsy. It can be said that none of the analyses have a 100% reliability since most of them can present false negatives; therefore, the best way to diagnose celiac disease up to now is through a combination of different tests (Immunoglobulin A and small intestinal biopsy).

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“…Certaines formes asymptomatiques, ou infracliniques de la MC, sont plus fré quemment associé es à des FCS, contrairement aux formes symptomatiques [115]. L'existence d'une MC doit ainsi être suspecté e chez les femmes sujettes aux FCS ré pé té es, même si elles ne pré sentent aucun symptô me de malabsorption [116]. Une é tude cas-té moin retrouve un risque de FCS multiplié par 8,90 (IC 95 % = 1,19-66,3) chez 94 patientes MC non traité es par rapport aux femmes sans MC [117].…”

Section: Maladie Coeliaque Et Grossesseunclassified

“…Dans une é tude prospective, 13 femmes atteintes de MC ayant pré senté 22 FCS ont é té suivies pendant dix ans aprè s leur mise sous ré gime sans gluten : six d'entre elles ont mené des grossesses à terme sans aucune FCS [116].…”

Section: Efficacite´du Re´gime Sans Gluten Sur La Survenue Des Fausseunclassified

Nutrition et fausses couches spontanées : une revue de la littérature

Benammar¹,

Sermondade

Faure

et al. 2012

Gynécologie Obstétrique & Fertilité

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Effect of Gluten-Free Diet on Pregnancy Outcome in Celiac Disease Patients with Recurrent Miscarriages

Abstract: GFD seems to favor a positive outcome of pregnancy in most CD patients with recurrent miscarriage.

Cited by 36 publications

References 23 publications

Recurrent miscarriage: causes, evaluation and management

Recurrent miscarriage: causes, evaluation and management

Tools Used to Measure the Physical State of Women with Celiac Disease: A Review with a Systematic Approach

Nutrition et fausses couches spontanées : une revue de la littérature

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