Effect of Glycerol Administration on ECochG and VEMP Findings in Individual with Meniere's Disease

Nagarajan, Pooja; Thangaraj, M.

doi:10.1007/s12070-021-02856-7

Cited by 1 publication

(2 citation statements)

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“…The subgroup without nystagmus nor EH had normal hearing and inner ear function, with all cases having hearing levels ≤7 dB and hearing fluctuations within 20 dB. The results of the inner ear function tests such as GVEMP and electrocochleography ( 15 , 16 , 23 ) showed positive findings of EH in nearly half of the cases.…”

Section: Resultsmentioning

confidence: 94%

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Stratification of patients with Menière’s disease based on eye movement videos recorded from the beginning of vertigo attacks and contrast-enhanced MRI findings

Ueno,

Imai,

Higashi-Shingai

et al. 2024

Front. Neurol.

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PurposeDiagnosis of Menière’s disease (MD) relies on subjective factors and the patients diagnosed with MD may have heterogeneous pathophysiologies. This study aims to stratify MD patients using two objective data, nystagmus videos and contrast-enhanced magnetic resonance imaging (CE-MRI).MethodsThis is a retrospective cross-sectional study. According to the Japan Society for Equilibrium Research criteria (c-JSER), adults diagnosed with definite MD and who obtained videos recorded by portable nystagmus recorder immediately following vertigo attacks and underwent CE-MRI of the inner ear were included (ss = 91). Patients who obtained no nystagmus videos, who had undergone sac surgery, and those with long examination intervals were excluded (n = 40).ResultsThe gender of the subjects was 22 males and 29 females. The age range was 20–82 y, with a median of 54 y. Endolymphatic hydrops (EH) were observed on CE-MRI in 84% (43 patients). Thirty-one patients had unilateral EH. All of them demonstrated EH on the side of the presence of cochlear symptoms. The number of patients who had both nystagmus and EH was 38. Five patients only showed EH and 5 patients only exhibited nystagmus, while 3 patients did not have either. Of the 43 nystagmus records, 32 showed irritative nystagmus immediately after the vertigo episode. The direction of nystagmus later reversed in 44% of cases over 24 h.ConclusionPatients were stratified into subgroups based on the presence or absence of EH and nystagmus. The side with cochlear symptoms was consistent with EH. The c-JSER allows for the diagnosis of early-stage MD patients, and it can be used to treat early MD and preserve hearing; however, this approach may also include patients with different pathologies.

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Section: Resultsmentioning

confidence: 94%

“…We presented the clinical examination data for each patient in the subgroup with nystagmus but without EH in Table 4 . The fluctuating range of hearing test results, GVEMP, and electrocochleography findings are highly specific for EH ( 15 , 16 , 23 ). Cases with more markedly positive results are shown in the upper row of Table 4 .…”

Section: Discussionmentioning

confidence: 99%