“…A decrease in the number of ova fertilized and transferable embryos at high doses of exogenous gonadotrophins has also been reported in other reports in both sheep (Moor et al, 1985) and cattle (McGowan et al, 1983;Donaldson and Ward, 1985;Donaldson et al, 1986). It has been demonstrated that high levels of gonadotrophins alter endocrine profiles (Quirke and Hanrahan, 1975;Whyman and Moore, 1980 ;McNatty et al, 1982), biochemical functions of oocytes (Moor et al, 1985) and sperm transport (Armstrong and Evans, 1984). All this may negatively influence the number and quality of fertilized ova.…”