Effect of Graphene Oxide/Hydroxyapatite fine-grained AZ91D on blood compatibility and cytocompatibility

Abstract

Magnesium alloy has excellent physical and mechanical properties and is expected to become a new generation of medical degradable materials. In this paper, the blood compatibility analysis of Graphene Oxide(GO)/Hydroxyapatite(HA)-AZ91D was carried out to improve the blood compatibility of magnesium alloy materials. AZ91D was used as the control group and GO/HA-AZ91D was used as the experimental group. The two samples were studied in vitro by hemolysis rate test, cell proliferation test, NO release and T-AOC test. The results combined with the work of the research group showed that the blood compatibility and cell compatibility of the GO/HA-AZ91D group were significantly improved, providing an effective idea for future corrosion resistant coatings on magnesium alloys.

Engineering Wet‐Resistant and Osteogenic Nanocomposite Adhesive to Control Bleeding and Infection after Median Sternotomy

“…The hemolysis test is a relatively simple but reliable method to estimate the blood compatibility of substances. [ 71 ] According to the standard (ASTM: F 756‐00), if the ratio of hemolysis of materials is below 2% and above 5%, those materials are considered non‐hemolytic and hemolytic, respectively. If the hemolysis activity falls between 2 and 5%, the substance is categorized as slightly hemolytic.…”