Effect of Growth Hormone Exon-5 Polymorphism on Growth Traits, Body Measurements, Slaughter and Carcass Characteristics, and Meat Quality in Meat-Type Lambs in Turkey

Abstract

This study examined the relationship between GHE5 polymorphisms and growth and carcass characteristics of meat-type sheep breeds reared in Turkey. A total of 202 lambs were tested, consisting of five breeds. By SSCP analysis and nucleotide sequencing, 14 nucleotide changes (12 substitutions and two deletions) were identified in four variants of GHE5. In the coding region of GHE5, five substitutions occur, including c.1588C>Y(C/T) (Ala160Val), c.1603A>M(A/C), c.1604G>S(G/C) (Lys165Thr), c.1606A>W(A/T) (Gln166Leu), and c.1664C>Y(C/T). P3 female and P1 male lambs had the highest rump height at weaning, whereas P3 females and P2 males had the highest chest depth (p < 0.05). At yearling, P1 variant lambs have longer body length (BL; p < 0.05), wider leg circumferences, and thinner cannon bone perimeter (CBP) (p > 0.01), in contrast to P2 variant lambs, which have a shorter BL and thicker CBP. Furthermore, P2 had a greater percentage of neck, shoulder, and leg, P1 had a greater percentage of loin, and P3 had a greater percentage of rack, but there was no significant difference between them. A marker-assisted selection approach can be used to improve sheep carcass quality traits by taking advantage of the nucleotide substitutions found on GHE5 and the detected differences between variants.

Genetic polymorphism of the growth hormone gene and their effects on growth metrics in the Assam Hill and Sirohi goats under subtropical climatic condition

“…In contrast to our observations, Pandya et al (2021) found that at six months of age, goats with BB genotypes had a superior body mass (P < 0.05) than those with AB genotypes in Surti Goats Singh et al (2015). observed similar ndings for body length in Sirohi and Barbari goats across all ages; however, statistical analysis failed to reveal signi cantly differ The same ndings were reported byEsen and Elmac (2022), who found that yearling lambs with the P1 variant of the growth Hormone Exon-5 (GHE5) gene have a higher body length (BL), wider leg girth, and lean cannon bone periphery (CBP) (P > 0.05), in comparison to lambs with the other variant (P2), whose body length is shorter and CBP is thicker Selionova et al (2022). revealed a favourable connection between the molecular marker among MSTN, HEG1, FGF10, FGF14, GHRH, and SLAIN genes linked to live body mass at age four months old.…”