Effect of guanidinoacetic acid and betaine supplementation in soybean meal-based diets on growth performance, muscle energy metabolism and methionine utilization in the bullfrog Lithobates catesbeianus

Lin, Jianwen; Zhang, Chunxiao; Lu, Kangle; Song, Kai; Wang, Ling

doi:10.1016/j.aquaculture.2020.736167

Cited by 21 publications

(5 citation statements)

References 57 publications

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“…We found that supplementing 0.2% GAA into the diet improved meat quality (muscle glycogen, CK, LDH, CV-IV, drip loss, shear force, and the L * , a * and b * values of beef) through increasing the Jinjiang bulls' antioxidant abilities. This result is consistent with the outcomes of supplementing GAA into the feed of other breeds of animals, such as growing-finishing gilts (6), broiler chickens (4, 33), fishes (3), bullfrogs (34)(35)(36), and sheep (37)(38)(39); nonetheless, the most effective dose differed between species.…”

Section: Gaa On Energy Buffering and Meat Qualitysupporting

confidence: 79%

“…These outcomes are positive for the consumer. These results are similar to the effects of dietary GAA in Angus bulls (24), sheep (37)(38)(39), finishing pigs (1, 2), broiler chickens (33), and bullfrogs (35,36), demonstrating that supplementing GAA into the diet could produce effects similar for both ruminant and non-ruminant animals.…”

Section: Gaa On Energy Buffering and Meat Qualitysupporting

confidence: 70%

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Effects of Dietary Guanidinoacetic Acid on the Feed Efficiency, Blood Measures, and Meat Quality of Jinjiang Bulls

Liang

Xin

et al. 2021

Front. Vet. Sci.

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An experiment was conducted to determine the effects of supplementing the diet of Jinjiang bulls with guanidinoacetic acid (GAA) on their feed efficiency [feed efficiency were evaluated with feedlot average daily gain (ADG), average daily feed intake (ADFI), and feed-to-gain ratio (F:G)], blood measures, and meat quality. Forty-five Jinjiang bulls (24 ± 3 months old and 350.15 ± 30.39 kg by weight) were randomly distributed among five experimental groups (each n = 9) and each group was randomly fed with one of five diets (concentrate: roughage ratio of 60:40): (1) control; (2) 0.05% GAA; (3) 0.1% GAA; (4) 0.2% GAA; and (5) 0.4% GAA, respectively. After a 52-days feeding trial, five bulls from the control group and five bulls from the optimal GAA supplementing group were randomly selected and slaughtered for collection of the longissimus thoracis (LT) and semitendinosus (SM) muscles to determine meat quality. The results showed that dietary GAA improved the ADG, decreased the value of F:G, and affected blood measures and antioxidant variables. Supplementing 0.2% GAA into the diet was optimal for feeding efficiency and most of the measured blood measures. Supplementing 0.2% GAA into the diet increased the a* (redness) values, and b* (yellowness) values, and the amount of creatine kinase (CK), muscle glycogen, creatinine (CRE), and laminin (LN) in LT muscles. However, it decreased the drip loss, L* (lightness) value, and lactate dehydrogenase (LDH) content of LT muscles. Drip loss and shear force decreased in SM muscles, as did the amount of type IV collagen (CV–IV). In conclusion, supplementing 0.2% GAA into the diet could enhance feed efficiency to improve beef growth and meat quality.

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Section: Gaa On Energy Buffering and Meat Qualitysupporting

confidence: 79%

Section: Gaa On Energy Buffering and Meat Qualitysupporting

confidence: 70%

Effects of Dietary Guanidinoacetic Acid on the Feed Efficiency, Blood Measures, and Meat Quality of Jinjiang Bulls

Liang

Xin

et al. 2021

Front. Vet. Sci.

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“…(Xia et al, 2019). In the current study, L. lactis supplementation improved growth performance, feed efficiency, and nitrogen retention of bullfrogs, and the increase in nitrogen retention was consistent with the trend in whole-body protein content, which agrees with our previous bullfrog study (Lin et al, 2021). This result indicated that the protein synthesis in bullfrogs might be stimulated by L. lactis treatment.…”

Section: Discussionsupporting

confidence: 91%

“…Quantitative PCR was performed on ABI StepOne Plus (Thermal Cycler, United States). The primers of the gene (Supplementary Table 2) and PCR amplification program were designed as our previous research on bullfrogs (Ding et al, 2019;Lin et al, 2021). The relative expression levels of genes were calculated using 2 − Ct method.…”

Section: Quantitative Real-time Pcrmentioning

confidence: 99%

Effects of Supplementing Intestinal Autochthonous Bacteria in Plant-Based Diets on Growth, Nutrient Digestibility, and Gut Health of Bullfrogs (Lithobates catesbeianus)

Wang

Zhang

et al. 2021

Front. Microbiol.

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Poor utilization efficiency of plant protein diets always leads to intestinal barrier dysfunction and growth inhibition in animals. Probiotics have shown promise in improving growth performance and gut health of the host. However, obtaining the host-beneficial probiotic from thousands of bacterial phylotypes is challenging. Here, four intestinal autochthonous bacteria were isolated from fast-growing bullfrog after a 60-day feeding on a soybean meal (SM)-based diet. Another feeding trial was conducted to evaluate the effects of supplementing these strains in an SM-based diet on growth, nutrient digestibility, immunity, and gut health of bullfrog. A high-SM basal diet was used as a non-supplemented control group (NC), and four other diets were prepared by supplementing the basal diet with 1 × 107 CFU/g of Bacillus siamensis, Bacillus tequilensis (BT), Bacillus velezensis, and Lactococcus lactis (LL). Results showed that weight gain, feed efficiency, nitrogen retention, and apparent digestibility coefficients of dry matter and protein were significantly higher in the LL group compared with the NC group (p < 0.05). Furthermore, compared with the NC group, both BT and LL groups showed markedly higher jejunal protease and amylase activities, serum complement 4 and immunoglobulin M levels, jejunal muscularis thickness (p < 0.05), and up-regulated expression of il-10 and zo-1 genes (p < 0.05). High-throughput sequencing revealed higher abundances of Bacillus and Cetobacterium in BT and LL groups, respectively, accompanied with decreased abundances of Enterobacter and Escherichia–Shigella. Besides, KEGG pathways related to metabolisms were significantly enhanced by the LL diet relative to the NC diet (p < 0.05). Overall, the beneficial effects of two frog-derived probiotics were determined: supplementation of L. lactis in SM-based diet promoted growth and nutrient digestibility; both B. tequilensis and L. lactis supplementation improved immune response and intestinal barrier function of bullfrogs.

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“…Introducing a new protein source in the fish diet might interfere with diet acceptability; therefore, feed attractants/ stimulants could be used to improve feed intake and diet acceptability. A well‐known feeding stimulant is betaine (Lin et al, 2021) that was formerly proved to increase feed intake and enhance growth performance through its methyl donor properties and its role in lipid metabolism (Luo et al, 2011; Elolimy et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Effect of poultry offal silage with or without betaine supplementation on growth performance, intestinal morphometry, spleen histomorphology of Nile tilapia (Oreochromis niloticus) fingerlings

Eissa

Yusuf

Younis

et al. 2021

Animal Physiology Nutrition

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Fishmeal (FM) is the main protein source in fish feed. However, it is quite expensive due to its limited resources. Therefore, finding a dietary alternative to the FM to sustain fish production is crucial, and the current study was performed to assess the impact of poultry offal silage (POS) with or without betaine supplementation; as an effective and cheaper alternative to FM; on feed efficiency, growth performance, spleen morphology and intestinal morphometry of Nile tilapia (Oreochromis niloticus) fingerlings. Four dietary treatments were formulated: (1) FM based diet, (2) FM‐B; FM diet +0.7% betaine, (3) POS diet and (4) POS‐B; POS diet +0.7% betaine. Each dietary treatment consisted of three replicates (n = 10/replicate), and the experiment was continued for 16 weeks. By the end of the experiment, spleen and intestine specimens were collected from 15 fish (n = 5/replicate) for histopathological assessment. The results were statistically analysed using GLM procedures of SAS 9.4. Feed efficiency increased in both POS‐B and FM‐B groups (p = 0.01), while body weight and body weight gain showed only weak tendencies towards an increase (p = 0.10 and 0.12, respectively). The villi length was the highest in POS‐B fed group (p < 0.01). In addition, melanomacrophage centres of the spleen increased in both betaine‐supplemented groups (p < 0.01). From our findings, we conclude that betaine supplementation with poultry offal silage improved production performance and immune status of Nile tilapia fish.

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Effect of guanidinoacetic acid and betaine supplementation in soybean meal-based diets on growth performance, muscle energy metabolism and methionine utilization in the bullfrog Lithobates catesbeianus

Cited by 21 publications

References 57 publications

Effects of Dietary Guanidinoacetic Acid on the Feed Efficiency, Blood Measures, and Meat Quality of Jinjiang Bulls

Effects of Dietary Guanidinoacetic Acid on the Feed Efficiency, Blood Measures, and Meat Quality of Jinjiang Bulls

Effects of Supplementing Intestinal Autochthonous Bacteria in Plant-Based Diets on Growth, Nutrient Digestibility, and Gut Health of Bullfrogs (Lithobates catesbeianus)

Effect of poultry offal silage with or without betaine supplementation on growth performance, intestinal morphometry, spleen histomorphology of Nile tilapia (Oreochromis niloticus) fingerlings

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