Effect of Gum-Chewing after Cesarean Section on Gastrointestinal Function Recovery: A Systematic Review and Meta-Analysis of Randomized Trials

Zhang, Liu; Heng, Yanlin; Hu, Hanqing; Liang, Xin

doi:10.4236/ym.2019.32009

Cited by 5 publications

(3 citation statements)

References 19 publications

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“…Zu San Li and Nei Guan were acupunctured to accelerate the gastrointestinal motility in children and adjust the content of hormone and gastric acid [18,19]; meanwhile, Yin Ling Quan and Nei Ting of children were acupunctured to invigorate spleen to eliminate dampness and disperse stagnated hepatoqi. Also, the TCM plasters contained evodia rutaecarpa, dried ginger, and rhizoma corydalis were used, with the functions of promoting qi circulation to relieve pain, warming stomach for dispelling cold, and recuperating depleted yang and invigorating pulse beat, and after herbal combination, they worked on the ganshu, xinshu, and other spots and strengthened the stimulus of acupuncture to children [20][21][22]. TCM emphasizes the dialectical treatment for this category of diseases, so the dialectical treatment of acupuncture is extremely important in treating FD, which can improve the clinical treatment outcome to some extent.…”

Section: Discussionmentioning

confidence: 99%

Clinical Effect of Acupuncture Combined with Traditional Chinese Medicine Application on the Treatment of Functional Dyspepsia in Children and the Influence on Serum 5-HT and NO Levels

Li¹,

Nie²,

Chen³

2022

Computational Intelligence and Neuroscience

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Objective. To explore the clinical effect of acupuncture combined with traditional Chinese medicine (TCM) application on the treatment of functional dyspepsia (FD) in children and the influence on serum 5-HT and NO levels. Methods. 94 FD children admitted to the pediatric department of our hospital from March 2019 to March 2020 were selected as the research object and divided into the study group (n = 45) and reference group (n = 49) by the number table method. The routine Western medicine therapy was given to the reference group and the combination therapy of acupuncture and TCM application was given to the study group to analyze the effect of different therapies on FD children by detecting their serum 5-hydroxytryptamine (5-HT) and nitric oxide (NO) levels and electrogastrogram (EGG) before and after treatment. Results. The sex ratio, mean age, mean duration of disease, mean weight, mean BMI value, and residence of children in the two groups were not significantly different ( P > 0.05 ); after treatment, the study group obtained significantly lower symptom scores and shorter disappearance time of clinical symptoms when comparing with the reference group ( P < 0.001 ); the total clinical effective rate of the study group was significantly higher than that of the reference group ( P < 0.05 ); the treated serum 5-HT and NO levels of children in both groups were significantly lower than those before treatment ( P < 0.05 ), and in the between-group comparison, those of the study group were significantly lower ( P < 0.05 ); and the treated AP, FP, and normal slow wave ratio of gastric antrum and body were significantly higher in the study group than in the reference group ( P < 0.05 ). Conclusion. The combination therapy of acupuncture and TCM application is a reliable method for improving the clinical symptoms in FD children. This strategy greatly reduces the levels of serum factors in child patients and shortens the corresponding treatment time. Further research will be conducive to establishing a better solution for such patients.

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Section: Discussionmentioning

confidence: 99%

Clinical Effect of Acupuncture Combined with Traditional Chinese Medicine Application on the Treatment of Functional Dyspepsia in Children and the Influence on Serum 5-HT and NO Levels

Li¹,

Nie²,

Chen³

2022

Computational Intelligence and Neuroscience

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“…Zhang, L et al, conducted a meta-analysis on a total of 13 RCTs which included 2233 patients. The results showed that chewing gum after cesarean delivery can effectively shorten the recovery time of bowel sounds, passage of flatus and first defecation [11] . Ajuzieogu, O.V.…”

Section: Discussionmentioning

confidence: 96%

A randomised comparative clinical study of the efficacy of ondansetron versus chewing gum for prevention of PONV in patients undergoing elective caesarean

Jain¹

2020

Int. J. Adv. Acad. Stud.

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Aim: to compare the ondansetron versus chewing gum for prevention of post-operative nausea and vomiting in patients undergoing elective LSCS. Material and methods: This was prospective Randomized trial done in the Department of Anesthesia…………….. A total of 120 patients for elective caesarean delivery were included in the study. Patients in Group I were given one strip of sugar free gum to be chewed for 30 minutes every eighth hourly. Patients randomized to Group-II received Inj. Ondansetron 4mg intravenously immediately after cesarean section. The relief of PONV as graded on a four-point verbal descriptive scale, and Five point Likert scale for acceptability, 3) Use of rescue medication for the first 24 hours after surgery 4) Sedation, as assessed with RAMSAY sedation scale and 5) Time to first flatus. Results: 2 patient in chewing gum group and 19 patients in Ondansetron group had episodes of nausea at 6 th hour postoperatively, whereas 2 patient in chewing gum group and 10 patients in Ondansetron group had PONV at 12 th hour. However, rescue medication was not required for these patients. It was observed that there was statistically significant difference between the two groups at 6 th and 12 th hour where the maximum number of events of PONV had occurred. On the scale for relief of PONV, it was observed that there was full resolution of PONV in more number of patients in chewing gum group than in the Ondansetron group. In the Likert scale response, the patients were more comfortable in the chewing gum group than in Ondansetron Group. Our data shows a beneficial effect of gum chewing in terms of better relief of post-operative nausea and shorter mean time intervals to passage of flatus (21.42 versus 30.49 hours) and acceptability. Conclusion: chewing gum is considered safe, well accepted better alternative to Ondansetron for the treatment of PONV in this randomized controlled study undergoing cesarean delivery under spinal anaesthesia. It also results in rapid resumption of intestinal motility, with potential impact on reducing the overall healthcare costs in case of routine implementation.

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“…The results showed that chewing gum after cesarean delivery can effectively shorten the recovery time of bowel sounds, passage of flatus and first defecation. 6 Ajuzieogu, O.V. et al conducted a study to evaluate the effect of chewing gum on post-operative ileus in 200 women who underwent cesarean sections and found that there was a statistically significant earlier onset of bowel sounds in the chewing group when compared to the control.…”

Section: Discussionmentioning

confidence: 99%

Comparison of ondansetron versus chewing gum for prevention of post operative nausea and vomiting in patients undergoing elective LSCS: A randomised control trial

Madhumala¹,

Rohit²,

M³

et al. 2020

IJCA

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Background: Pregnant women are always considered full stomach with high incidence of nausea and vomiting. Anti-emetic efficacy of Ondansetron has been proved in various studies. The aim of this present study is to evaluate efficacy and safety of chewing gum as an alternative to Ondansetron in prevention of postoperative nausea and vomiting (PONV) in parturients undergoing elective LSCS under spinal anesthesia. Materials and Methods: One hundred pregnant women who were found eligible as per inclusion and exclusion criteria were randomized into two equal groups by simple randomization into Group A (n=50) who were given sugar free chewing gum which was to be chewed for 30 minutes three times a day starting immediately after cesarean section and Group B (n=50) who received Inj. Ondanse tron 4mg twice a day post operatively. The outcome measures were episodes of post-operative nausea and vomiting at 6, 12, 18 and 24 hours in both groups, relief of PONV and acceptability of treatment. The secondary outcome measures time to first flatus. Statistical analysis was done through relevant tests using SPSS 16.0. Results: There was no statistically significant difference between the two groups in terms of demographic characteristics such as age, gravidity parity, duration of surgery and type of cesarean section. The incidence of nausea and vomiting was significantly less in Group A compared with Group B at 6 and 12 hours post operatively (p < 0.001). There was no significant difference of this variable at 18 and 24 hours in both groups. The mean average of the first passage of flatus in group A was 20.3±2.01 hours versus 29.6±2.51 hours in Group B (P<0.0001) was significantly shorter compared to the group B. Conclusion: Gum chewing after cesarean section is safe, well tolerated, and acceptable for prevention of post-operative nausea and vomiting and rapid resumption of intestinal motility and has potential impact on reducing the overall healthcare costs in case of routine implementation.

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Effect of Gum-Chewing after Cesarean Section on Gastrointestinal Function Recovery: A Systematic Review and Meta-Analysis of Randomized Trials

Cited by 5 publications

References 19 publications

Clinical Effect of Acupuncture Combined with Traditional Chinese Medicine Application on the Treatment of Functional Dyspepsia in Children and the Influence on Serum 5-HT and NO Levels

Clinical Effect of Acupuncture Combined with Traditional Chinese Medicine Application on the Treatment of Functional Dyspepsia in Children and the Influence on Serum 5-HT and NO Levels

A randomised comparative clinical study of the efficacy of ondansetron versus chewing gum for prevention of PONV in patients undergoing elective caesarean

Comparison of ondansetron versus chewing gum for prevention of post operative nausea and vomiting in patients undergoing elective LSCS: A randomised control trial

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