The study was conducted at the Agricultural Research Station in Shandaweel, Sohag Governorate, Egypt. (latitude of 26.33° N and longitude of 31.41° E) in the 2020/2021 and 2021/2022 planting seasons, to evaluate the effects of three concentrations of the chemical ripener " Ethrel" (0.6, 0.8 and 1.0 liter/fed) sprayed on the leaves, in addition to control treatment (without spraying) on yield and quality of tow sugarcane varieties [the commercial variety (G.T. 54-9) and the promising one (G. 2004-27) in addition to (G. 2005-47) genotype]. A randomized complete block design was used in a split-plot arrangement was used. The results showed that the sugarcane varieties differed markedly in all studied traits. G.T. 54-9 variety superior in stalk diameter and sugar yield/fed in both seasons as well as cane yield/fed in the 1st one, while, G.2004-27 variety recorded the highest stalk and most number of millable canes/fed in both seasons as well as cane yield/fed in the 1st season, on the other hand, G.2005-47 genotype was superior in brix, sucrose, purity and sugar recovery% in both seasons. The results also showed that adding 1.0 liter/fed of Ethrel spray to the cane leaves caused an increase in brix, sucrose, purity and sugar recovery% as well as sugar yield/fed, compared to the untreated (control). On the contrary, the treatments with Ethrel concentrations led to a decrease in the height and diameter of the stalk as well as cane yield. However, the increase (%) in quality and sugar yield was more than the decrease in cane yield. Therefore, Ethrel addition led to an increase in quality and sugar yield at concentration of 1.0 liter/fed "E3". Under conditions of this work, it was found that growing all studied sugarcane varieties and spraying them with 1.0 l/fed of Ethrel ripener can be recommended for the maximum sugar production.