Effect of hazelnut on serum lipid profile and fatty acid composition of erythrocyte phospholipids in children and adolescents with primary hyperlipidemia: A randomized controlled trial

Deon, Valeria; Bò, Cristian Del; Guaraldi, Federica; Abello, Francesca; Belviso, Simona; Porrini, Marisa; Riso, Patrizia; Guardamagna, Ornella

doi:10.1016/j.clnu.2017.05.022

Cited by 27 publications

(31 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the differences in fatty acid profile between small and large kernels were much less than the differences between macadamia cultivars [27,72,73] and between tree-nut species including almond, hazelnut, macadamia, pecan, pistachio and walnut [4,9]. All these nuts are considered beneficial for reducing the risk of cardiovascular disease because of their high levels of unsaturated fatty acids [1,2,7,10,14,[74][75][76][77][78][79]. Table 2.…”

Section: Fatty Acid Compositionmentioning

confidence: 99%

Relationships between Nut Size, Kernel Quality, Nutritional Composition and Levels of Outcrossing in Three Macadamia Cultivars

Richards

Kämper

Trueman

et al. 2020

Plants

View full text Add to dashboard Cite

Tree nuts play an important role in healthy diets, but their economic value and nutritional quality may be affected by their size and paternity. We assessed relationships between nut size and kernel recovery, the incidence of whole kernels, fatty acid composition and mineral nutrient concentrations in three macadamia cultivars, "Daddow", "816" and "A4". We determined to what extent differences in nut size and quality were the result of different levels of cross-or self-paternity. Small nuts of all cultivars had lower kernel recovery than large nuts, and small nuts provided lower incidence of whole kernels in "Daddow" and "A4". Small kernels had a lower relative abundance of the saturated fatty acid, palmitic acid, in all cultivars and higher relative abundance of the unsaturated fatty acid, oleic acid, in "Daddow" and "A4". Small kernels had higher concentrations of many essential nutrients such as nitrogen and calcium, although potassium concentrations were lower in small kernels. Most nuts arose from cross-pollination. Therefore, nut size and kernel quality were not related to different levels of cross-and self-paternity. Identified cross-paternity was 88%, 78% and 90%, and identified self-paternity was 3%, 2% and 0%, for "Daddow", "816" and "A4", respectively. Small macadamia kernels are at least as nutritious as large macadamia kernels. High levels of cross-paternity confirmed that many macadamia cultivars are predominantly outcrossing. Macadamia growers may need to closely inter-plant cultivars and manage beehives to maximise cross-pollination.Plants 2020, 9, 228 2 of 14 also a valuable source of calcium, iron and zinc, which can be absorbed insufficiently during phases of high dietary demand such as infancy, childhood, adolescence, pregnancy and breastfeeding [16][17][18][19][20][21].The fatty acid composition and nutrient concentrations of tree-nut kernels can vary greatly among cultivars [9,[22][23][24][25][26][27][28]. Fatty acid composition and nutrient concentrations can also vary within almond or pistachio cultivars because of differences in the pollen parentage of individual kernels [22][23][24][25]29,30]. For example, self-pollinated kernels of some almond cultivars have lower oleic:linoleic acid ratios than cross-pollinated kernels [25,29]. In addition, self-pollinated kernels of some almond, chestnut and hazelnut cultivars are smaller than cross-pollinated kernels [22,[31][32][33]. Such effects of the paternal genetic background on the size or quality of the embryo are termed "xenia", and xenic effects are common in fruit and nut crops [34]. Therefore, maximising both yield and human-health benefits may depend upon ensuring high levels of cross-pollination in tree-nut orchards.Relationships between kernel size, nutritional composition, and cross-or self-paternity are poorly understood for some nuts, including the subtropical tree nut, macadamia (Macadamia integrifolia, M. tetraphylla and hybrids). Macadamia flowers are bee-pollinated and partially self-incompatible [35][36][37][38][39][40][41][42]...

show abstract

Section: Fatty Acid Compositionmentioning

confidence: 99%

Relationships between Nut Size, Kernel Quality, Nutritional Composition and Levels of Outcrossing in Three Macadamia Cultivars

Richards

Kämper

Trueman

et al. 2020

Plants

View full text Add to dashboard Cite

show abstract

“…To explore the role of tree nuts on lipid parameters within hyperlipidemic population, it was performed a systematic review of dose-response clinical trials 18-20 and controlled interventional trials. 20-46…”

Section: Methodsmentioning

confidence: 99%

“…Some findings indicated that hazelnuts exert a favorable impact on blood lipid concentrations. Deon et al 25 have noticed a significant reduction in LDL-c and elevation in HDL/LDL-c ratio after consuming hazelnuts either with skin or without skin (15-30 g/d) during a period of 8 weeks. Mercanligil et al 30 found that hazelnut has a lipid-lowering capacity, as they have observed that the daily inclusion of hazelnut (40 g) have a positive alteration in blood lipids among hypercholesterolemic men and thereby favorably influencing the coronary heart disease risk.…”

Section: Hazelnutmentioning

confidence: 99%

Effect of Tree Nuts Consumption on Serum Lipid Profile in Hyperlipidemic Individuals: A Systematic Review

Altamimi

Zidan

Badrasawi

2020

Nutr Metab Insights

View full text Add to dashboard Cite

Many epidemiological studies have regularly connected nuts intake with decreased risk for coronary heart disease. The primary mechanism by which nuts protect against cardiovascular disease is through the improvement of lipid and apolipoprotein profile. Therefore, numerous dietary intervention studies investigated the impact of nut consumption on blood lipid levels. Many studies have shown that nut intake can enhance the lipid profile in a dose-response way among individuals with increased serum lipids. This systematic review examines the effectiveness of nuts on the lipid profile among patients with dyslipidemia from different age groups. A total of 29 interventional studies from 5 databases met the inclusion criteria. In all, 20 studies were randomized controlled clinical trials, whereas 9 were crossover-controlled clinical trials. Participants included in the studies were different in terms of age, sex and, serum lipid profile. The studies were inconsistent in the type of tree nuts, duration, dose, and the nut forms. All studies indicated changes in the lipid profile after the intervention particularly on the total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides, total cholesterol/high-density lipoprotein. Interventional periods ranged from 3 weeks up to 12 months with doses ranged from 15 to 126 gm. In conclusion, this review provides an evidence of favorable effect of nuts consumption of serum lipid profile.

show abstract

“…To ensure that this happened, each subject received 28 packets, each filled with a day’s ration of nuts, one for each day of the study. This regimen of nuts and number of nuts was devised based on previous studies with each of the following nuts [ 7 - 9 ].…”

Section: Methodsmentioning

confidence: 99%

A Pilot Study on the Effects of Nut Consumption on Cardiovascular Biomarkers

Adashek

Redding

2020

Cureus

View full text Add to dashboard Cite

Background: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in the United States and changes in lifestyle can minimize the likelihood of succumbing to heart disease. Anti-inflammatory agents are commonly used to reduce the chronic inflammatory state behind the pathogenesis of CVD. Multiple studies have been published correlating nut consumption with a reduction in both heart attacks and strokes. The goal of this study is to determine to what extent the consumption of almonds, hazelnuts, and walnuts have on the blood markers associated with cardiac disease and inflammation. Methods: This was a six-week study in which subject’s baseline values act as controls. Fasting blood draws occurred at week 0, week 2, and after four weeks of intervention (week 6). All participants had undesirable lipid profiles and no medications related to heart disease. Results: Total cholesterol (TC): high-density lipoprotein (HDL-C) ratio was lowered a statistically significant amount at the six-week time point (3.89 ± 0.74) compared to both the zero-week (4.93 ± 1.16, p < 0.01) and two-week (4.63 ± 1.20, p < 0.5) timepoints. Low-density lipoprotein (LDL) measurements were lowered a statistically significant amount at the six-week time point (135.6 ± 15.0 mg/dL) compared to the zero-week (159.7 ± 12.3 mg/dL, p < 0.01). Erythrocyte sedimentation rate (ESR) was lowered a statistically significant amount at six-week time point (10.44 ± 5.05 mm/h) compared to the zero-week (14.44 ± 5.12 mm/h, p < 0.01). Conclusions: Blood markers associated with CVD specifically and the general marker for inflammation associated with many chronic diseases can be favorably modified with the consumption of specific nuts as demonstrated by this study.

show abstract

Effect of hazelnut on serum lipid profile and fatty acid composition of erythrocyte phospholipids in children and adolescents with primary hyperlipidemia: A randomized controlled trial

Cited by 27 publications

References 42 publications

Relationships between Nut Size, Kernel Quality, Nutritional Composition and Levels of Outcrossing in Three Macadamia Cultivars

Relationships between Nut Size, Kernel Quality, Nutritional Composition and Levels of Outcrossing in Three Macadamia Cultivars

Effect of Tree Nuts Consumption on Serum Lipid Profile in Hyperlipidemic Individuals: A Systematic Review

A Pilot Study on the Effects of Nut Consumption on Cardiovascular Biomarkers

Contact Info

Product

Resources

About