Effect of herbal beverages of Foeniculum vulgare and Cymbopogon proximus on inhibition of calcium oxalate renal crystals formation in rats

Ibrahim, Faten Y.; El-Khateeb, A. Y.

doi:10.1016/j.aoas.2013.07.006

Cited by 25 publications

(15 citation statements)

References 22 publications

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“…A small placenta results in reduced uterine blood flow to the placenta and consequently to the fetuses, which is the major determinant of fetal growth retardation [25]. Phenol is one of the aqueous extract of Cymbopogon proximus [3]. Phenols are natural products originated by various plants.…”

Section: Discussionmentioning

confidence: 99%

“…Halfa-bar acted through relaxation of the smooth muscle fibers without abolishing the propulsive movement of the tissue, thus, it is usually used in the expulsion of renal and ureteric calculi [1]. Terpenes, tannins, flavonoids, saponins, alkaloids, carbohydrate or glycosides, and phenolic glycosides are the phytochemical compositions which are found in the aqueous extract of C. proximus [2], [3]. Even for efficient and documented herbal medicinal products, the toxicity can be relatively undetected; unlike, the conventional drugs research and development, the toxicity of usual herbal medicines is not often estimated [4], [5], [6].…”

Section: Introductionmentioning

confidence: 99%

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Implications arising from the use of Cymbopogen proximus ; proximal on placenta of pregnant Albino rats

Omar

El-Din

Abdelrahman

2016

Braz. arch. biol. technol.

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Halfa-bar (Cymbopogon proximus), is an aromatic grass widely growing in Upper Egypt. This herb is recommended for medical purposes as an effective diuretic, renal or abdominal antispasmodic agent. Objectives of this study: Evaluate the potential effects of Halfa-bar on the pregnant albino rats during the gestation period. Material and methods: The virgin female rats mated with male then the pregnant rats treated orally with Human Equivalent Dose (HED) of the proximol which equivalent 0.05 mg/ kg rat from 5th -18th Gestational Day (GD). At day 20 of pregnancy, all rats were anesthetized and killed to obtained maternal -fetal data (placenta

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Implications arising from the use of Cymbopogen proximus ; proximal on placenta of pregnant Albino rats

Omar

El-Din

Abdelrahman

2016

Braz. arch. biol. technol.

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“…C. proximus has been used for several decades by the inhabitants of these regions as a diuretic and antispasmodic agent due to its potent ability to induce smooth-muscle relaxation [19]. C. proximus reportedly possesses many biological properties, including hypoglycemic, antipyretic, bronchodilation, antibacterial, anticonvulsant, and antiemetic activities [15,[20][21][22][23]. Interestingly, C. proximus has been shown to exhibit a hypotensive effect in normotensive rats and protect against nitro-L-arginine methyl ester (L-NAME)-induced hypertension [23,24].…”

Section: Introductionmentioning

confidence: 99%

Cymbopogon Proximus Essential Oil Protects Rats against Isoproterenol-Induced Cardiac Hypertrophy and Fibrosis

et al. 2020

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Cymbopogon proximus (Halfabar), a wild plant that is usually used in folk medicine due to its diuretic and antispasmodic effects, was shown to exhibit several cardiovascular protective actions such as antidiabetic, antihypertensive, antioxidant, and antinflammatory effects. However, no reports are available regarding the investigation of the role of Cymbopogon proximus essential oil on cardiac hypertrophy. Therefore, the goals of the present study were to find whether Cymbopogon proximus could alleviate isoproterenol induced‐cardiac hypertrophy and to determine the underlying molecular mechanisms. For this purpose, male albino rats were treated daily with either Cymbopogon proximus essential oil (800 μl/kg/day, ip), isoproterenol (5 mg/kg/day, ip), or the combination of both. Oil administration was started four days prior to isoproterenol administration and continued concurrently thereafter for another three days. All animal groups were euthanized 24 hours after the last dose of treatment. Thereafter, the hearts were harvested and heart weight to body weight (HW:BW) ratios were measured and sections of hearts were stained with Masson's trichrome and H&E to assess cardiac fibrosis and morphology. Our results showed that isoproterenol alone resulted in a significant increase in HW:BW ratio and marked myocardial fibrosis in treated rats. On the other hand, treatment with Cymbopogon proximus essential oil significantly reduced the isoproterenol‐mediated increase in HW:BW ratio by 55%. However, oil treatment did not affect isoproterenol mediated‐increase in myocardial fibrosis. Conclusion Cymbopogon proximus essential oil partly protects against isoproterenol‐induced cardiac hypertrophy with no effect on cardiac fibrosis. These findings provide support for the promising therapeutic effects of Cymbopogon proximus on cardiac diseases. This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.

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“…Ginger has a sugar component consisting of glucose, fructose, galactose and sucrose. Whereas for fennel seed extract, it is thought that it only gives a small contribution to TSS coffee due to other dominant components in fennel seeds such as crude fiber, protein, fat and carbohydrate content (Ibrahim and Ayman, 2013). The equation obtained from the model is as follows:…”

Section: Total Response Of Solid Solutionmentioning

confidence: 99%

Tengger Herbal (concocted) coffee formulation with fennel seed (Foeniculum vulgare) and ginger (Zingiber officinale) extract

Wijana

Perdani

Febrianata

et al. 2018

AFSSAAE

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Coffee is a drink suitable for consumption in cold areas. Bromo tourist area is a producer of fennel plants that can be used as a drink to warm the body. This study used Robusta coffee, fennel seed and ginger extract as the basic ingredients for making herbal coffee. The study aimed to obtain a herbal coffee formulation based on fennel seed and ginger extract to enhance and sustain food diversity in Bromo. This study employed the Response Surface Methodology (RSM) method with two factors (i.e. the proportion of Robusta coffee and the proportion of fennel seed and ginger extract) and three responses (i.e. pH, TSS, color L). Selection of the best treatment was carried out by using the effectiveness index method. The best treatment results and optimal solutions for RSM were then tested for antioxidant activity by using DPPH method. The results showed that optimal formulation of coffee (based on RSM) in a proportion of Robusta coffee of 12.50 g (proportion of fennel seed and ginger extract of 10.00 g) has a pH of 5.93, total soluble solids of 12.00 °Brix and L value of26.56 with IC 50 value of 75.50 ppm. Whereas, the best organoleptic result was found from the first treatment, in the proportion of 14.00 g Robusta coffee (with fennel seed and ginger extracts of 10.00 g with a pH value of 5.73, total soluble solids of 13.00°Brix, L * value of 25.06 and IC 50 of 69.50 ppm).

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Effect of herbal beverages of Foeniculum vulgare and Cymbopogon proximus on inhibition of calcium oxalate renal crystals formation in rats

Cited by 25 publications

References 22 publications

Implications arising from the use of Cymbopogen proximus ; proximal on placenta of pregnant Albino rats

Implications arising from the use of Cymbopogen proximus ; proximal on placenta of pregnant Albino rats

Cymbopogon Proximus Essential Oil Protects Rats against Isoproterenol-Induced Cardiac Hypertrophy and Fibrosis

Tengger Herbal (concocted) coffee formulation with fennel seed (Foeniculum vulgare) and ginger (Zingiber officinale) extract

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