Effect of Hibiscus rosa sinensis aqueous extract treatment on biochemical parameters in diabetic pregnant rats

Silva, Thaís Leal; Afiune, Luana Alves de Freitas; Souza, Rafaianne Queiroz de Moraes; Soares, Thelma Shirlen; Carneiro, Thalita Bohnen; Américo, Madilene Francely; Campos, Kleber Eduardo de; Volpato, Gustavo Tadeu

doi:10.1186/1758-5996-7-s1-a77

Cited by 2 publications

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“…A decrease in the triglycerides and ALT levels were observed in pregnant diabetic Wistar rats fed with H. rosasinensis aqueous extract at a dose of 100 mg/kg from day 0 to 7 of pregnancy, 200 mg/kg from day 8 to 14 and 400 mg/kg from day 15 to 20. However, no effect on glycemia was observed in this study (Silva et al, 2015).…”

Section: Antihypercholesterolemic Effectscontrasting

confidence: 74%

Hibiscus rosa-sinensis L. (red Hibiscus) Tea, Can It Be Used as A Home-Remedy to Control Diabetes and Hypercholesterolemia?

et al. 2021

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According to traditional medicine, Hibiscus is used to treat hypertension, heart diseases and many other ailments. Commercially available Hibiscus tea is prepared with H. sabdariffa and is expensive. H. rosasinensis is the common variety which is abundant in tropical home-gardens, however the scientific data are lacking on the effects. The present review focuses on the available scientific data on the effects of H. rosasinensis on controlling diabetes and hypercholesterolemia. The endeavour was to identify whether H. rosasinensis flower petals as a ‘tea’ is effective for diabetic and hypercholesterolemic patients. Medical databases such as MEDLINE, BMC, BMJ, research gate, Mendelay literature search database, Google scholar and the general engine Google were searched from November 2018 to April 2019. Search was carried out using keywords such as “Hibiscus rosasinensis”, “antidiabetic effects”, “antihyperlipidemic effects”, “toxic effects”, “anti-inflammatory effects”, “phytochemicals in Hibiscus” etc. Data were critically analyzed to assess whether the effective doses of the research studies on a par with the doses present in H. rosasinensis teas. We found thirty-nine journal articles fulfilled the criteria. The data were categorized and extracted on uses of H. rosasinensis, anti-diabetic effects, anti-inflammatory effects, anti-hypercholesterolemic effects and its phytochemicals. The review revealed that the dose of H. rosasinensis petals present in a home-made Hibiscus tea is theoretically sufficient to elicit anti-hyperglycemic and anti-hyperlipidemic effects. Home-made Hibiscus tea is effective in controlling diabetes and hypercholesterolemia without causing acute toxicity.

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Section: Antihypercholesterolemic Effectscontrasting

confidence: 74%