Effect of high-fat diets on body composition, lipid metabolism and insulin sensitivity, and the role of exercise on these parameters

Coelho, Desiré; Pereira-Lancha, Luciana Oquendo; Chaves, Douglas Siqueira de Almeida; Diwan, Deepti; Ferraz, Rafael C.; Campos-Ferraz, Patrícia Lopes de; Poortmans, Jacques-Rémi; Lancha, Antônio Herbert

doi:10.1590/s0100-879x2011007500107

Cited by 72 publications

(55 citation statements)

References 60 publications

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“…High contents of lipid in human diet are principal sources of obesity and other relative diseases. Dietary fat composition can interfere in the development of obesity due to the specific roles of some fatty acids that have different metabolic activities, which can alter both fat oxidation and deposition rates, resulting in changes in body weight and/or composition (Coelho et al, 2011). H. sabdariffa, S. scabrum and B. alba have the higher fiber contents; the lower fiber contents were observed in C. olitorius extract.…”

Section: Nutritional Composition Of Aqueous Leavesmentioning

confidence: 99%

Phytochemical, nutritional and antioxidant capacity of five Ivorian edible leaves aqueous extracts

Konan¹,

Koffi²,

Cissé³

et al. 2016

J App Pharm Sci

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Boiled aqueous extract from five Ivorian edible leaves (Solanum scabrum, Ipomea batatas, Corchorus olitorius, Basella alba, Hibiscus sabdariffa) have been analyzed for their antioxidant contents, phytochemical and nutritional compositions. I. batata extract showed the highest amount of antioxidant (167.52 µg/100gTE), total polyphenol (34.18 mg/100 g TE) and total flavonoid (12.67 mg/100g TE). The higher energy value (225.5 kcal) was obtained in S. scrabrum extract. The highest amount of zinc and potassium were found in S. scrabrum extract (0.28 and 362.1 mg/100 g DW; respectively). Maximum amount of copper (1.16 mg/100 g DW) and calcium (777.9 mg/100 g DW) were obtained in H. sabdariffa extract. The highest content of iron (49.81 mg/100 g DW) and magnesium (201 mg/100 g DW) were observed in B. alba extract. The highest content of sodium (2.39 mg/100 g DW) was obtained in C. olitorius extract. All extracts contained secondary metabolites such as polyphenols (tannins, flavonoids), sterols and terpenes, which have medicinal potent.

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Section: Nutritional Composition Of Aqueous Leavesmentioning

confidence: 99%

Phytochemical, nutritional and antioxidant capacity of five Ivorian edible leaves aqueous extracts

Konan¹,

Koffi²,

Cissé³

et al. 2016

J App Pharm Sci

View full text Add to dashboard Cite

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“…A positive correlation has been observed between this dietary pattern and the development of insulin resistance, type 2 diabetes mellitus, and dyslipidemia 12 therefore, more susceptible to less availability of nitric oxide, an essential molecule in maintaining the erectile function 6 .…”

Section: Discussionmentioning

confidence: 99%

Lard and/or canola oil-rich diets induce penile morphological alterations in a rat model

et al. 2014

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PURPOSE:To investigate the effect of dietary lipid quantity and/or quality on penis morphology in adult rats. METHODS:Thirty-eight male Wistar rats were divided into 4 groups: normal lipid diet (NL), high-fat diet rich in saturated fatty acids (HF-S), high-fat diet rich in polyunsaturated fatty acids (HF-P), and high-fat diet rich in saturated and polyunsaturated fatty acids (HF-SP). Blood samples were collected and the penises were removed for histomorphometrical and immunohistochemical analysis. RESULTS:All high-fat diets promoted an increase in the body mass (p<0.0001). The HF-S and HF-SP groups presented hyperglycemia (p=0.0060), hyperinsulinemia (p=0.0030), and hypercholesterolemia (p=0.0020). Concerning the penis, the high-fat diets led to an increase in the collagen fibers (p<0.0001) and smooth muscle cell density area (p=0.0027), and a decline in the sinusoidal space density area (p<0.0001) and corpus cavernosum cell proliferation (p=0.0003). CONCLUSION:Diets rich in saturated and/or polyunsaturated fatty acids promoted overweight and induced penile changes in rodent models, which may lead to the development of erectile dysfunction.

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“…Diets rich in SFA and cholesterol are associated with factors that negatively affect metabolism and predispose individuals to the development of IR and type 2 diabetes mellitus [17]. On the other hand, the consumption of PUFAs has been considered a protective factor against the development of these changes [17].…”

Section: Discussionmentioning

confidence: 99%

Diets Rich in Saturated and Polyunsaturated Fatty Acids Induce Morphological Alterations in the Rat Ventral Prostate

et al. 2014

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AimTo evaluate the influence of dietary lipid quality on the body mass, carbohydrate metabolism and morphology of the rat ventral prostate.Materials and MethodsWistar rats were divided into four groups: SC (standard chow), HF-S (high-fat diet rich in saturated fatty acids), HF-P (high-fat diet rich in polyunsaturated fatty acids) and HF-SP (high-fat diet rich in saturated and polyunsaturated fatty acids). We analyzed body mass, fat mass deposits, plasma blood, insulin resistance and the ventral prostate structure.ResultsGroups that received high-fat diets were heavier and presented larger fat deposits than SC group. The HF-S and HF-SP groups had higher glucose, insulin and total cholesterol serum levels and insulin resistance compared with the SC. The acinar area, epithelium height and area density of the lumen were higher in the HF-SP than in the other groups. The epithelium area density and epithelial cell proliferation were greater in the HF-P and HF-SP than in the SC group. All of the groups that received high-fat diets had greater area density of the stroma, area density of smooth muscle cells and stromal cell proliferation compared with the SC group.ConclusionDiets rich in saturated and/or polyunsaturated fatty acids induced overweight. Independently of insulin resistance, polyunsaturated fatty acids increased prostate stromal and epithelial cell proliferation. Saturated fatty acids influenced only stromal cellular proliferation. These structural and morphometric alterations may be considered risk factors for the development of adverse remodeling process in the rat ventral prostate.

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Effect of high-fat diets on body composition, lipid metabolism and insulin sensitivity, and the role of exercise on these parameters

Cited by 72 publications

References 60 publications

Phytochemical, nutritional and antioxidant capacity of five Ivorian edible leaves aqueous extracts

Phytochemical, nutritional and antioxidant capacity of five Ivorian edible leaves aqueous extracts

Lard and/or canola oil-rich diets induce penile morphological alterations in a rat model

Diets Rich in Saturated and Polyunsaturated Fatty Acids Induce Morphological Alterations in the Rat Ventral Prostate

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