Effect of high intensity interval training on diabetic obese women with polyneuropathy: a randomized controlled clinical trial

Hamed, Nashwa Sayed; Raoof, Neveen Ahmad Latif Abdel

doi:10.7243/2055-2386-1-4

Cited by 14 publications

(12 citation statements)

References 32 publications

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“…The above-mentioned findings seem to be in conformity with the results of those studies in which HIT was accompanied by improving glycemic control in obese and/or patients with T2D (36)(37)(38). Several studies have recently demonstrated that SIT appeared to be a very timeefficient exercise regime that shared many of the metabolic adaptations as traditional endurance exercise training did (36,39,40).…”

Section: Discussionsupporting

confidence: 87%

The effects of 10-week different exercise interventions on Framingham risk score and metabolic syndrome severity scores in overweight women with type 2 diabetes

Banitalebi

Ghahfarrokhi

Faramarzi

et al. 2018

J Shahrekord Univ Med Sci

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Background and aims: Type 2 diabetes (T2D) is a strong independent risk factor for cardiovascular disease (CVD). The purpose of this study was to examine the effects of short sprint interval training (SIT) and combined aerobic + resistance training (A+R) on Framingham risk score (FRS) and metabolic syndrome severity scores (MetS score) in overweight women with T2D. Methods: In this single-blind randomized clinical trial,52 overweight females afflicted with T2D (aged 45-60 years, BMI>30 kg/m2, HbA1C ≥ 6.5%) were randomly assigned to either SIT (n = 17), combined training (n = 17), and control groups (n = 18). Interventions consisted of SIT or combined aerobic-strength training for 10 weeks. Data were analyzed using a paired t test to compare pretest and posttest results in each group. A one-way ANOVA was employed to compare the number of changes in the experimental and control training groups after 10 weeks. Results: The results indicated that there were significant differences between the groups in FRS (P = 0.001). However, no difference was found in Mets score (P = 0.160). In addition, significant differences were observed in FRS between SIT and combined training groups (P = 0.018) and also SIT and control groups (P = 0.001). Conclusion: The results highlighted that SIT as compared to the combined training could be an effective strategy to improve FRS and Mets score in women with T2D

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Section: Discussionsupporting

confidence: 87%

The effects of 10-week different exercise interventions on Framingham risk score and metabolic syndrome severity scores in overweight women with type 2 diabetes

Banitalebi

Ghahfarrokhi

Faramarzi

et al. 2018

J Shahrekord Univ Med Sci

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“…Our study’s IC intervention did not induce any changes in HOMA-IR, although it did result in modest improvements in muscle mass in the OW group ( Table 3 ). Our findings seem to be inconsistent with those of previous studies demonstrating that high-intensity training was accompanied by improved glycemic control in people with obesity and/or type 2 diabetes [ 43 , 44 ]. On the other hand, it should be recognized that the HOMA-IR assessment is not always sensitive to small but significant changes in insulin sensitivity [ 45 ].…”

Section: Discussioncontrasting

confidence: 99%

Effects of an Indoor Cycling Program on Cardiometabolic Factors in Women with Obesity vs. Normal Body Weight

Ratajczak¹,

Skrypnik

Krutki³

et al. 2020

IJERPH

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The study aimed to provide evidence on the impact of indoor cycling (IC) in reducing cardiometabolic risk factors. The study compares the effects of a 3 month IC program involving three 55 min sessions per week on women aged 40–60 years, with obesity (OW, n = 18) vs. women with normal body weight (NW, n = 8). At baseline and at the end of the study, anthropometric parameters, oxygen uptake (VO2 peak), and serum parameters: glucose, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG), insulin, human anti-oxidized low-density lipoprotein antibody (OLAb), total blood antioxidant capacity (TAC), thiobarbituric acid reactive substances (TBARS), endothelial nitric oxide synthase (eNOS), C-reactive protein (CRP), lipid accumulation product (LAP), and homeostasis model assessment of insulin resistance index (HOMA IR) were determined. Before the intervention, VO2 peak and HDL-C levels were significantly lower and levels of TG, LAP, insulin, HOMA-IR, and CRP were significantly higher in the OW group compared to those in the NW group. After the intervention, only the OW group saw a decrease in body mass, total cholesterol, OLAb, TBARS, and CRP concentration and an increase in total body skeletal muscle mass and HDL-C concentration. In response to the IC training, measured indicators in the OW group were seen to approach the recommended values, but all between-group differences remained significant. Our results demonstrate that IC shows promise for reducing cardiometabolic risk factors, especially dyslipidemia. After 12 weeks of regular IC, the metabolic function of the OW group adapted in many aspects to be more like that of the NW group.

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“…Thus, one research [ 17 ] has demonstrated that total and abdominal fat loss seems to be lowered more by HIIT than traditional continuous endurance training. Additionally, 15 weeks of 3 weekly sessions of HIIT on bicycle ergometer among diabetic obese women with polyneuropathy were found to be distinctly effective in lowering waist circumference, neuropathic pain, and hyperglycaemia as opposed to moderate intensity aerobic training [ 78 ].…”

Section: Discussionmentioning

confidence: 99%

High Intensity Interval Training Improves Glycaemic Control and Pancreatic β Cell Function of Type 2 Diabetes Patients

et al. 2015

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Physical activity improves the regulation of glucose homeostasis in both type 2 diabetes (T2D) patients and healthy individuals, but the effect on pancreatic β cell function is unknown. We investigated glycaemic control, pancreatic function and total fat mass before and after 8 weeks of low volume high intensity interval training (HIIT) on cycle ergometer in T2D patients and matched healthy control individuals. Study design/method: Elderly (56 yrs±2), non-active T2D patients (n = 10) and matched (52 yrs±2) healthy controls (CON) (n = 13) exercised 3 times (10×60 sec. HIIT) a week over an 8 week period on a cycle ergometer. Participants underwent a 2-hour oral glucose tolerance test (OGTT). On a separate day, resting blood pressure measurement was conducted followed by an incremental maximal oxygen uptake (O2max) cycle ergometer test. Finally, a whole body dual X-ray absorptiometry (DXA) was performed. After 8 weeks of training, the same measurements were performed. Results: in the T2D-group, glycaemic control as determined by average fasting venous glucose concentration (p = 0.01), end point 2-hour OGTT (p = 0.04) and glycosylated haemoglobin (p = 0.04) were significantly reduced. Pancreatic homeostasis as determined by homeostatic model assessment of insulin resistance (HOMA-IR) and HOMA β cell function (HOMA-%β) were both significantly ameliorated (p = 0.03 and p = 0.03, respectively). Whole body insulin sensitivity as determined by the disposition index (DI) was significantly increased (p = 0.03). During OGTT, the glucose continuum was significantly reduced at -15 (p = 0.03), 30 (p = 0.03) and 120 min (p = 0.03) and at -10 (p = 0.003) and 0 min (p = 0.003) with an additional improvement (p = 0.03) of its 1st phase (30 min) area under curve (AUC). Significant abdominal fat mass losses were seen in both groups (T2D: p = 0.004 and CON: p = 0.02) corresponding to a percentage change of -17.84%±5.02 and -9.66%±3.07, respectively. Conclusion: these results demonstrate that HIIT improves overall glycaemic control and pancreatic β cell function in T2D patients. Additionally, both groups experienced abdominal fat mass losses. These findings demonstrate that HIIT is a health beneficial exercise strategy in T2D patients.Trial RegistrationClinicalTrials.gov NCT02333734 http://clinicaltrials.gov/ct2/show/NCT02333734

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Effect of high intensity interval training on diabetic obese women with polyneuropathy: a randomized controlled clinical trial

Cited by 14 publications

References 32 publications

The effects of 10-week different exercise interventions on Framingham risk score and metabolic syndrome severity scores in overweight women with type 2 diabetes

The effects of 10-week different exercise interventions on Framingham risk score and metabolic syndrome severity scores in overweight women with type 2 diabetes

Effects of an Indoor Cycling Program on Cardiometabolic Factors in Women with Obesity vs. Normal Body Weight

High Intensity Interval Training Improves Glycaemic Control and Pancreatic β Cell Function of Type 2 Diabetes Patients

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