Effect of honey and yogurt on vaginal candidiasis: A systematic review and meta- analysis of clinical trials

Karimi, Fatemeh Zahra; Maleki-Saghooni, Nahid; Miri, Hamid Heidarian; Moeindarbari, Somayeh; Moghaddam, Hamideh Yazdi

doi:10.29252/sjku.24.5.105

Cited by 2 publications

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“…In the current study honey cause inhabitation of colonization of Candida species which is consistent with the findings of the study of others. 13,[26][27][28][29][30][31][32] This effect is likely related to the antimicrobial effect of honey is due to its osmolality. The present findings demonstrate the effectiveness of honey on negative cultures of samples within 8 days after the intervention, while no effect was observed in the study of Shalev et al 27 It is assumed that difference is due to antimicrobial effect of honey.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Efficacy of Honey Gel and Clotrimazole Cream in the Treatment of Vaginal Candidiasis Signs: A Randomized Clinical Trial

et al. 2020

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Introduction Candida albicans is responsible for 85% to 95% of vaginal yeast infections. 1 Factors that cause an increased susceptibility to vulvovaginitis candidiasis (VVC) include: antibiotic therapy, pregnancy, uncontrolled diabetes mellitus, using oral contraceptives (especially high-dose formulations), immune suppressants, and synthetic clothing. 1-4 The most common signs of vaginal candidiasis are discharge, may be aqueous to thick and homogenous. There are vaginal burning, burning and sensitivity of the vulva. 1,4,5 Treatment agents include butoconazole, clotrimazole, miconazole and terconazole. The side effects of these treatments are headache, gastrointestinal disorders. 1,6-8 The incidence of Candida infections is escalating worldwide. The serious nature of these infections is compounded by increasing levels of drug resistance. 4 The increase in the resistance of antifungal has attracted the attention of the scientific community. 8 Honey as a medicine is being used thousands of years. If it is used alone or in combination with other substances in vagina to inhibit the growth of Candida laboratory and clinical results of honey in inhibiting the growth of various fungi such as Candida has been promising. 9-14 In Islam, honey strongly recommended for healing purposes. However, honey has a low use in modern medicine result of lack of scientific support, it has been observed that honey can be used to treatment liver, cardiovascular and gastrointestinal problems. Ancient Egyptians, Assyrians, Chinese, Greeks and Romans used honey for wounds and

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Section: Discussionmentioning

confidence: 99%

Comparison of the Efficacy of Honey Gel and Clotrimazole Cream in the Treatment of Vaginal Candidiasis Signs: A Randomized Clinical Trial

et al. 2020

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Comparison of the Efficacy of Honey and Clotrimazole Cream in the Vulvovaginal Candidiasis Treatment: A Systematic Review and Metaanalysis

Mirghafourvand

Mollazadeh-Narestan

Yavarikia

et al. 2023

CDTH

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Background: Vulvovaginal candidiasis (VVC) is a common fungal infection of the vaginal area affecting 75% of women at least once in their lifetime. However, there is no clear evidence helping to choose the most effective treatment method to improve the symptoms of VVC. Objective: The objective of this study was to compare the effect of using honey with clotrimazole on the treatment of symptoms of VVC. Methods: All databases in English (Embase, MEDLINE, ProQuest, Google Scholar, Scopus, Cochrane Library, and Web of Science) and Persian (Irandoc, SID, and Magiran) were searched without time limitation. Evaluation of studies in terms of bias was performed using the Cochrane handbook. Four clinical trials were included in the present systematic review; however, only three of them were included in the meta-analysis. Results: The results of the meta-analysis demonstrated that the rate of positive culture after treatment (RR: 2.35; 95%CI: 1.45 to 3.82) was significantly higher in the honey group than in the clotrimazole one. The frequency of itching after treatment (RR: 0.25, 95%CI: 0.12 to 0.49) was significantly lower in the honey-receiving group than in the clotrimazole one. However, there was no statistically significant difference in the incidence of other symptoms of VVC, including vaginal discharge (RR: 0.26, 95%CI: 0.02 to 2.75), vaginal burning (RR: 0.35, 95%CI: 0.03 to 3.80) and dyspareunia (RR: 0.64, 95%CI: 0.27 to 1.50) between groups. Conclusion: Due to the low quality of the studies, more clinical trial studies with stronger designs in this field are needed to clearly identify the therapeutic effects of honey on improving the symptoms of VVC.

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Effect of honey and yogurt on vaginal candidiasis: A systematic review and meta- analysis of clinical trials

Cited by 2 publications

References 0 publications

Comparison of the Efficacy of Honey Gel and Clotrimazole Cream in the Treatment of Vaginal Candidiasis Signs: A Randomized Clinical Trial

Comparison of the Efficacy of Honey Gel and Clotrimazole Cream in the Treatment of Vaginal Candidiasis Signs: A Randomized Clinical Trial

Comparison of the Efficacy of Honey and Clotrimazole Cream in the Vulvovaginal Candidiasis Treatment: A Systematic Review and Metaanalysis

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