Effect of Hormesis in Dunaliella viridis Teodor. (Chlorophyta) Under the Influence of Copper Sulfate

Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol

“…However, the pre-injections of several small doses of the copper sulfate, that caused chronic toxicity, can provide resistance to the subsequent injection of a lethal dose, so the hormesis effect was manifested [30].…”

“…Thus, salts of ethylenediaminetetraacetic acid (EDTA), which is a good chelating agent [29], or compounds that are donors of SHgroups are the most common antidotes for heavy metal ions [30].…”

“…Previously, it was shown that the hormesis effect of copper ions is determined by cooperative change in many, if not all protective systems of the body, which are characterized by the emergence [30].…”

“…Furthermore, administration of low doses of copper sulfate (LD 30 ) on a background of fungidol provides not only survival after subsequent lethal dose and but the increase of efficiency, body temperature and growth rate of these animals.…”

“…The first group: the intact controlanimals was injected normal saline solution in dose 0.5 ml per 100 g of body weight; the second group -animals to which was injected the copper sulfate intraperitoneally in dose 1 mg per 100 g body weight three times (once per 48 hours) in the morning before feeding. It corresponds to LD 30 . The interval between copper sulfate additions was 48 hours.…”