2022
DOI: 10.1136/bmjopen-2021-054876
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Effect of hyperbaric oxygen therapy on cognitive dysfunction induced by nitrous oxide abuse: protocol of a randomised, double-blinded, placebo-controlled trial

Abstract: IntroductionThe cognitive dysfunction associated with nitrous oxide abuse is gradually becoming a major global public health concern. Despite the increasing prevalence of nitrous oxide abuse, there are currently no authorised/approved treatment options. Hyperbaric oxygen therapy (HBOT) has been proven to be an efficient method to improve cognitive function. The current randomised, double-blinded, placebo-controlled trial will explore the effect of HBOT on cognitive dysfunction induced by nitrous oxide abuse.Me… Show more

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“…HBOT is a well-established treatment conducive to the recovery of cognitive function. 22 Evidence shows that HBOT can enhance neural plasticity and cognitive function in stroke patients. A clinical trial 23 cognitive improvement in dementia patients 24 and to some extent benefit patients with vascular dementia.…”
Section: Discussionmentioning
confidence: 99%
“…HBOT is a well-established treatment conducive to the recovery of cognitive function. 22 Evidence shows that HBOT can enhance neural plasticity and cognitive function in stroke patients. A clinical trial 23 cognitive improvement in dementia patients 24 and to some extent benefit patients with vascular dementia.…”
Section: Discussionmentioning
confidence: 99%