Effect of Immunoglobulin Y on Growth Performance and Blood Immunological Parameters in Holstein Calves

Abstract

A total of fourteen, 1-wk-old male Holstein calves were allotted into two groups consisted of control (CON) and IGY which was orally administrated with immunoglobulin yolk (IgY) for 1wk. Calves in both groups were provided with milk replacer according to feeding program and had ad libitum access to timothy hay for the entire experimental period (7wks). At 0, 7 and 49 day of experiment, blood samples were collected from the jugular vein of calves to investigate blood biochemical profiles and the differential count (%) of white blood cell (WBC). We also monitored growth performance and colony forming unit (CFU) of fecal microbial population in calves. The adminstration of IgY in calves did not affect body weight and weight gain during 49 days feeding trial compared with control group. The CFU of E. coli and Lactobacilli in the feces of calves were not significantly affected by IgY treatment, whereas the score of the calf scours during day 43 to 49 in IgY group showed a significant (P<0.05) solid type. There were no differences in plasma biochemical components including total protein, albumin, immunoglobulin and the other indicators. As for WBC differential count (%), there was no statistical difference in the percentages of neutrophil, lymphocyte, monocyte, eosinophil and basophil at 0, 7 and 49 days after the oral supplementation of IgY. In conclusion, the oral supplementation of IgY as an immunostimulant did not affect growth performance, fecal microbial population, blood biochemical profile and WBC differential count in Holstein calves.

Alternatives to conventional antibiotics for the prevention and treatment of commonly occurring diseases in feedlot cattle

“…A large number of compounds can act as immunostimulants and the effects of many have been studied in cattle, including bacterial fractions, 110–114 β‐glucans from the cell walls of bacteria and fungi, 115–117 viral fractions, 118,119 the anthelmintics levamisole 120–125 and thiabendazole, 126 immune complexes and various foreign proteins 127,128 and inorganic compounds such as the synthetic polyprenol, dihydroheptaprenol 129 and the xanthine derivative, pentoxil 130…”

“…Base tissue concentrations of immunoenhancers are essential for normal function, and in situations where pathogen challenge is increased, tissue concentrations of these greater than the requirement for the prevention of the clinical signs of deficiency can be beneficial. 109 A large number of compounds can act as immunostimulants and the effects of many have been studied in cattle, including bacterial fractions, [110][111][112][113][114] β-glucans from the cell walls of bacteria and fungi, [115][116][117] viral fractions, 118,119 the anthelmintics levamisole [120][121][122][123][124][125] and thiabendazole, 126 immune complexes and various foreign proteins 127,128 and inorganic compounds such as the synthetic polyprenol, dihydroheptaprenol 129 and the xanthine derivative, pentoxil. 130 An in vitro response in the activity of the polymorphonuclear cells (neutrophils and macrophages) that act as the first line of defence in cell-mediated immunity to the administration of any of the antigenic compounds listed above is inevitable in healthy animal tissues dependent on dose and is therefore largely meaningless to field applications.…”

Effects of Supplementing Herbs on Growth Performances, Blood Composition and Diarrhea in Hanwoo Calves

“…생후 6개월 이내의 어린 송아지는 다양한 환경과 모축에서 나오는 병원체들에 감 염됨으로서 이들 병원체들이 일으키는 다양한 질병이 발생되고 있다 (Martin & Meek, 1986;Kang et al, 1998 (Kim, et al, 1990). 이러한 송아지 설사병을 예방치료하기 위한 방법으로 냉동보관 초유, 주사용 IgG 용액, 건조초유, 난황항체(IgY) 등 여러 가지가 있지만 (Jung, et al, 2009), 현재 시중에서 판매․유통되고 있는 초유와 IgY는 일시적인 효과를 나타낼 뿐 장기적인 치료효과는 거 의 없다고 (Osame, et al, 1991) 하였다. 한편 우리나라는 금년 7 월부터 사료내의 항생제 사용을 전면금지(농림수산식품부 고시.…”

Effects of Supplemented Resveratrol on In Vitro Ruminal Fermentation and Growth Performance of Hanwoo Calves

“…Some prior studies suggest that feeding resveratrol to ruminants affects digestion and immunity [ 18 ]. Therefore, the immunity of calves affects weaning age and carcass body weight which affects the farm’s profitability [ 19 , 20 ].…”