Effect of Immunotherapy on the Quality of Life in Patients with Allergic Rhinitis Sensitive to House Dust Mite

Abstract

Background: Allergic rhinitis (AR) has serious effects on the quality of life (QoL) of patients. It leads to impairments in daily activities, work and school performance, and practical problems. Objectives: To assessed the effects of HDM immunotherapy on the QoL in patients with AR. Methodology: The QoL was assessed in 120 AR patients sensitive to HDM using Rhinoconjuntivitis Quality of Life Questionnaire (RQLQ). Patients received HDM-specific immunotherapy for 6 months after which the QoL was assessed again. Results: showed that rhinorrhea was the most common symptom (92.5%) while nasal itching was the least (55.8 %). After immunotherapy, a significant number of patients showed improvement of nasal obstruction and rhinorrhea. A significant improvement in the RQLQ score was also observed regarding activity limitation, sleep problems, nose symptoms, eye symptoms, practical problems and emotional function (p < 0.5). Conclusion: HDM immunotherapy improves the QoL in AR patients sensitive to HDM allergens.