Effect of in ovo manganese injection on the embryonic development, antioxidation, hatchability, and performances of offspring broilers under normal and high temperatures

In‌ ovo feeding of nutraceuticals and its role in adjusting the gastrointestinal tract, antioxidative properties, immunological response, and performance in poultry: An updated review

“…Also, Han et al (2022) postulated that IOF of l-leucine had no significant influence on BWG and relative weights of liver, heart and bursa of Fabricius; however, it improved the relative weight of spleen in broilers at 39 days of age. Similarly, Geng et al (2022) noted that IOF of 25.0 μg Mn did not affect BWG, ADFI, FCR, mortality, dressing %, breast muscle %, thigh muscle %, abdominal fat %, pH and colour of breast and thigh meats.…”

“…Also, Krisnan et al (2021) indicated that IOF of 0.15 ppm of organic or inorganic Se on 18 day of incubation elevated serum GSH-Px activity at 18 days of chicken age. Moreover, Geng et al (2022) noted that delivery of Mn (6.25, 12.5, 25.0, or 50.0 μg) via the in ovo route elevated SOD mRNA expression in the embryonic heart and might alleviate oxidative stress. Furthermore, Shokraneh et al (2020) showed that IOF of 500 µg nano-Zn on day 17 of embryonic development increased serum activities of GSH-Px and SOD.…”

“…Several recent publications documented the positive effect of IOF of antioxidants, vitamins, and minerals on hatchability and chick quality characteristics (El-Deep et al 2020;Hajati et al 2021;Geng et al 2022). Asa et al (2022) observed that IOF of a mixture of antioxidants and carbohydrates improved hatching %, chick weight, chick quality characteristics, appearance and eye condition, and activity of new-born chicks.…”

“…documented that IOF of 12 or 25 mg of l-ascorbic acid on day 18 of embryonic development increased serum concentrations of l-ascorbic acid and SOD and lowered serum MDA concentration. Similarly,Zhang et al (2019) indicated that IOF of l-ascorbic acid (12 mg) increased plasma SOD and decreased MDA concentrations in 42-day-old broilers.Numerous studies proved that IOF of antioxidant minerals, including Se(El-Deep et al 2020;Krisnan et al 2021), Mn(Geng et al 2022), and Zn(Shokraneh et al 2020) improved the antioxidative status and reduced lipid peroxidation El-Deep et al (2020). demonstrated that IOF of 10, 20, or 30 μg of nano-Se on day 18 of embryonic development enhanced serum concentrations of total antioxidant capacity, GSH-Px, SOD, and CAT.…”

Metalloproteomic analysis of liver proteins isolated from broilers fed with different sources and levels of copper and manganese

“…Copper acts as a cofactor for several important enzymes, such as CuZn-superoxide dismutase (CuZn-SOD), cytochrome-c-oxidase (COX) and ceruloplasmin, which makes it essential in the elimination of free radicals, cellular respiration, and iron mobilization 3 . In the same way, manganese acts as a component of metalloproteins and an enzymatic cofactor, as it is fundamental in antioxidant defense, bone formation and metabolism of carbohydrates, amino acids, and cholesterol 4 – 6 .…”