Effect of Increasing Concentrations of Tween 80 and Sorbitol as Surfactants and Cosurfactans Against the Physical Stability Properties of Palm Oil Microemulsion

Abstract

Palm oil is one of the fatty oil can used as the oil phase in the microemulsion system. The purpose of this research was to identify the effect of increasing concentration of combination of surfactant and cosurfactant on the physical stability of palm oil microemulsion. This oil was formulated into microemulsion system by increasing concentration of combination of tween 80 and sorbitol (1:1) in various concentrations, which were 54%, 56%, 58% and 60% as surfactant and cosurfactant component. The evaluation included organoleptic, viscosity test, pH, density, surface tension and particle size and zeta potential test. The pH showed in the range 5.8 to 6.4. Viscosity value obtained between 637.47 to 808.20 Cps. Density measurement were between 1.1123 to 1.1235 g/ml. The results of surface tension obtained between 39.76 to 43.07 dynes/cm. The results of particle size measurement results obtained from 21.27 to 23.97 nm and the zeta potential between −10.28 to −18.03. It can be concluded that the increasing of concentration of surfactant and cosurfactant can improve physical stability of the microemulsion.

Insights from a Box–Behnken Optimization Study of Microemulsions with Salicylic Acid for Acne Therapy

“…Values of viscosity of 22.4-26.69 cP were reported in rheological study of O/W microemulsions with minoxidil, being associated with the composition based on a total amount of S/CoS mixture of 53% [83]. As the concentration of S/CoS blend increases between 54-60%, viscosity can attain 637.47-808.20 cP, as it was observed in the evaluation process of O/W microemulsions with palm oil 6%, without changing the model of viscosity [95]. In-depth studies were conducted to assess rheological properties of O/W microemulsions using a mixture of Tween 80/PG (2:1) (10-30%) as a powerful solubilizer for cinnamon essential oil 2-5%.…”

“…In pendant drop model, γ L/G varied between 32.57-37.36 mN/m, describing stability of the systems characterized by low superficial tensions, and consequently low interfacial tensions between oil and water phases. In the study of Yati K. et al, the values of γ L/G reported after applying De Nouy ring method for microemulsions stabilized with Tween 80 and sorbitol, were placed between 39.76-43.4 mN/m [95]. Likewise, in CA model γ L/G was evaluated as a parameter implied in drop dynamics, succeeding adhesion promotion.…”