Effect of Inquiry-Based Stress Reduction on Well-being and Views on Risk-Reducing Surgery Among Women WithBRCAVariants in Israel

Abstract

IMPORTANCEThe high risk for breast and ovarian cancers conferred by being a carrier of BRCA1 or BRCA2 germline variant can negatively impact physical and psychological well-being. Novel nonpharmacological interventions on well-being in women with BRCA variants have rarely been reported. OBJECTIVE To determine the effect of a 12-week inquiry-based stress reduction (IBSR) program on psychological well-being, sleep quality, psychosocial variables, and attitudes toward risk-reducing surgical procedures among women in Israel who carried BRCA variants. DESIGN, SETTING, AND PARTICIPANTS This randomized clinical trial had a 12-week intervention period and a 12-week follow-up period. It was conducted between April 1, 2017, and July 31, 2020.

The lifestyle factors of physical activity and diet balance associated with HPV infection in China: The cross-sectional study

“…This obvious paradox has led to increased targeting of diet balance patterns as a risk factor. In addition, three other risk factors that indicate a plausibly precancerous condition are sleep quality and psychosocial variables such as depression and anxiety ( 9 ).…”

The Lifestyle Factors of Physical Activity and Diet Balance associated with HPV Infection

“…This obvious paradox has led to increased targeting of diet balance patterns as a risk factor. In addition, three other risk factors that indicate a plausibly precancerous condition are sleep quality and psychosocial variables such as depression and anxiety [6]. However, relatively few studies have focused on connecting these lifestyle behaviors with HPV infection or HPV persistent infections.…”