2013
DOI: 10.1167/iovs.13-12409
|View full text |Cite
|
Sign up to set email alerts
|

Effect of Instillation of Eyedrops for Dry Eye on Optical Quality

Abstract: Quantitative serial measurement of HOAs and forward light scatter showed that the temporal reduction in optical quality may be attributed mainly to increased HOAs after instillation of highly viscous 0.3% sodium hyaluronate ophthalmic solution and to increased forward light scatter after instillation of 2% rebamipide ophthalmic suspension in healthy subjects.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

7
39
0
1

Year Published

2014
2014
2021
2021

Publication Types

Select...
5
3

Relationship

2
6

Authors

Journals

citations
Cited by 45 publications
(47 citation statements)
references
References 42 publications
7
39
0
1
Order By: Relevance
“…19 However, a higher concentration of sodium hyaluronate does not necessarily lead to better outcomes; eye drops with a high viscosity cause irregularities in the tear film and blurring of vision. 20 Similar findings of a deteriorated image quality were reported in other studies, particularly at 1 minute after eye drop instillation, 21,22 although the increased tear meniscus measurements obtained by OCT in our study were found to last longer. Wang et al 23 used custom-built real-time OCT to prove that the tear film thickness remained high for at least 5 minutes after the instillation of artificial tears, with a significant correlation between the lower TMH and TMA.…”
Section: Discussionsupporting
confidence: 91%
“…19 However, a higher concentration of sodium hyaluronate does not necessarily lead to better outcomes; eye drops with a high viscosity cause irregularities in the tear film and blurring of vision. 20 Similar findings of a deteriorated image quality were reported in other studies, particularly at 1 minute after eye drop instillation, 21,22 although the increased tear meniscus measurements obtained by OCT in our study were found to last longer. Wang et al 23 used custom-built real-time OCT to prove that the tear film thickness remained high for at least 5 minutes after the instillation of artificial tears, with a significant correlation between the lower TMH and TMA.…”
Section: Discussionsupporting
confidence: 91%
“…Their findings were consistent with previous findings by Hiraoka et al regarding antiglaucoma eye drops 71. However, this study only tested healthy subjects 77. A study by Lekhanont et al 80 reviewed the impact of a single instillation of 0.18% sodium hyaluronate artificial tear on HOAs in dry eye patients, both at baseline and up to 120 min after instillation.…”
Section: Properties Of the Tear Film And On Short-term Qovsupporting
confidence: 89%
“…Koh et al reported the effect of viscosity and suspensibility of eye drops used for dry eye treatment on ocular HOAs and forward light scattering 77. They compared 0.3% sodium hyaluronate ophthalmic solution (with high viscosity), 3% diquafosol ophthalmic solution and 2% rebamipide ophthalmic suspension (with high suspensibility) and saline.…”
Section: Properties Of the Tear Film And On Short-term Qovmentioning
confidence: 99%
See 1 more Smart Citation
“…Moreover, the short-term influence of therapeutic eye drops for dry eye and glaucoma has been quantified by measuring the time course of HOAs or light scattering in healthy subjects. [66][67][68][69] These studies demonstrated that a temporal decrease in optical quality after the instillation of viscous ophthalmic solution or gel-forming solution may be primarily attributed to an increase in HOAs that is possibly caused by increased corneal irregularities. Furthermore, a temporal decrease in optical quality after the instillation of ophthalmic suspension may be primarily attributed to increased light scattering that is possibly caused by white particles.…”
Section: Accommodationmentioning
confidence: 91%