Effect of Intensive vs Standard Blood Pressure Treatment Upon Erectile Function in Hypertensive Men: Findings From the Systolic Blood Pressure Intervention Trial

Foy, Capri G.; Newman, Jill C.; Russell, Greg; Berlowitz, Dan R.; Bates, Jeffrey T.; Burgner, Anna; Carson, Thaddeus Y; Chertow, Glenn M.; Doumas, Michael; Hughes, Robin Y; Kostis, John B.; Buren, Peter Van; Wadley, Virginia G.

doi:10.1016/j.jsxm.2019.11.256

Cited by 8 publications

(6 citation statements)

References 37 publications

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“…The relationship between hypertension and ED is difficult to establish given the coexistence of many risk factors in the majority of men with ED. In contrast with previous reports, some studies showed that high BP was not correlated with an increased risk of ED 70 and that BP control did not result in better outcomes of erectile function 71 even after 6 years of follow‐up. 72 …”

Section: The ‘Complicated Role’ Of Complications and Cofactors In The...contrasting

confidence: 79%

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

Defeudis

Mazzilli

Tenuta

et al. 2021

Diabetes Metabolism Res

128

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Diabetes mellitus (DM), a chronic metabolic disease characterised by elevated levels of blood glucose, is among the most common chronic diseases. The incidence and prevalence of DM have been increasing over the years. The complications of DM represent a serious health problem. The long-term complications include macroangiopathy, microangiopathy and neuropathy as well as sexual dysfunction (SD) in both men and women. Erectile dysfunction (ED) has been considered the most important SD in men with DM. The prevalence of ED is approximately 3.5-fold higher in men with DM than in those without DM. Common risk factors for the development of DM and its complications include sedentary lifestyle, overweight/ obesity and increased caloric consumption. Although lifestyle changes may help improve sexual function, specific treatments are often needed. This study aims to review the definition and prevalence of ED in DM, the impact of DM complications and DM treatment on ED and, finally, the current and emerging therapies for ED in patients with DM.

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Section: The ‘Complicated Role’ Of Complications and Cofactors In The...contrasting

confidence: 79%

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

Defeudis

Mazzilli

Tenuta

et al. 2021

Diabetes Metabolism Res

128

View full text Add to dashboard Cite

show abstract

“…For example, hypertension significantly increases sexual dysfunction (odds ratio = 2.789, p = 0.002) compared with the normotensive group [ 28 ]. However the effect of intensive blood pressure lowering is moderate (p for interaction = 0.0016, [ 29 ]). Diabetes is also one of the most frequent organic causes of sexual dysfunction affecting around 20 to 36% of subjects [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

COPD burden on sexual well-being

Zysman

Rubenstein

Guillou³

et al. 2020

Respir Res

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Background Sexual function is often affected in patients suffering from chronic diseases especially chronic obstructive pulmonary disease (COPD). However, the effect of COPD on sexual satisfaction is underappreciated in clinical practice. The aim of this study is to evaluate the impact of COPD on patient’s sexuality and the explanatory variables of sexual dissatisfaction. Methods Questionnaires were emailed to participants and they submitted their responses on the Santé Respiratoire France website. Data about sexual well-being (Arizona Sexual Experience Scale, ASEX), Quality of life (VQ11), anxiety, depression (Hospitalized anxiety and depression, HAD) and self-declared COPD grade were collected. Results Seven hundred and fifty one subjects were included and were characterized as follows: women—51%, mean age—61 years, in a couple—62% and 70%—retired. Every grade of COPD was represented. Out of 751 participants, 301 participants (40%) had no sexual activity and 450 (60%) had sexual activity. From the 450 participants, 60% needed to change their sexual life because of their disease (rhythm, frequency and position). Subjects often used medications to improve sexual performance (43% used short-acting bronchodilator and 13% -specific erectile dysfunction drugs). ASEX questionnaire confirmed patients’ dissatisfaction (diminution of sexual appetite for 68% and sexual desire for 60%) because of breathlessness and fatigue. Eighty one percent of the responders had an altered quality of life (VQ11 mean score 35) and frequent suspected anxiety or depression (HAD mean score 10.8). Ninety percent declared that sexual dysfunction had never been discussed by their doctors, while 36% of patients would have preferred to undergo a specialized consultation. Conclusion Sexual dysfunction is frequent among COPD patients and leads to an altered well-being, however being a cultural taboo, it remains frequently neglected. Sexual guidance should be a part of patient’s consultations improve quality of sexual life.

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“…For example, hypertension significantly increases sexual dysfunction (odds ratio = 2.789, p = 0.002) compared with the normotensive group [28]. However the effect of intensive blood pressure lowering is moderate (p for interaction = 0.0016, [29]). Diabetes is also one of the most frequent organic causes of sexual dysfunction affecting around 20 to 36% of subjects [30].…”

Section: Discussionmentioning

confidence: 98%

COPD burden on sexual well-being

Rubenstein

Zysman

Guillou³

et al. 2020

Clinical Problems

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Background: Sexual function is often affected in patients suffering from chronic diseases especially chronic obstructive pulmonary disease (COPD). However, the effect of COPD on sexual satisfaction is underappreciated in clinical practice. The aim of this study is to evaluate the impact of COPD on patient's sexuality and the explanatory variables of sexual dissatisfaction. Methods: Questionnaires were emailed to participants and they submitted their responses on the Santé Respiratoire France website. Data about sexual well-being (Arizona Sexual Experience Scale, ASEX), Quality of life (VQ11), anxiety, depression (Hospitalized anxiety and depression, HAD) and self-declared COPD grade were collected. Results: Seven hundred and fifty one subjects were included and were characterized as follows: women-51%, mean age-61 years, in a couple-62% and 70%-retired. Every grade of COPD was represented. Out of 751 participants, 301 participants (40%) had no sexual activity and 450 (60%) had sexual activity. From the 450 participants, 60% needed to change their sexual life because of their disease (rhythm, frequency and position). Subjects often used medications to improve sexual performance (43% used short-acting bronchodilator and 13%-specific erectile dysfunction drugs). ASEX questionnaire confirmed patients' dissatisfaction (diminution of sexual appetite for 68% and sexual desire for 60%) because of breathlessness and fatigue. Eighty one percent of the responders had an altered quality of life (VQ11 mean score 35) and frequent suspected anxiety or depression (HAD mean score 10.8). Ninety percent declared that sexual dysfunction had never been discussed by their doctors, while 36% of patients would have preferred to undergo a specialized consultation. Conclusion: Sexual dysfunction is frequent among COPD patients and leads to an altered well-being, however being a cultural taboo, it remains frequently neglected. Sexual guidance should be a part of patient's consultations improve quality of sexual life.

show abstract

Effect of Intensive vs Standard Blood Pressure Treatment Upon Erectile Function in Hypertensive Men: Findings From the Systolic Blood Pressure Intervention Trial

Cited by 8 publications

References 37 publications

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

COPD burden on sexual well-being

COPD burden on sexual well-being

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