1971
DOI: 10.1097/00003086-197110000-00006
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Effect of Intra-articular Injection of Hyaluronic Acid on the Clinical Symptoms of Osteoarthritis and on Granulation Tissue Formation

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Cited by 210 publications
(85 citation statements)
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“…The most common side effects are local reactions of the knee such as swelling, pain, and increased warmth. This type of reaction typically lasts for 1 to 2 days [7]. With proper patient selection and injection technique, these injections are a viable treatment option for patients with early symptomatic knee OA.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The most common side effects are local reactions of the knee such as swelling, pain, and increased warmth. This type of reaction typically lasts for 1 to 2 days [7]. With proper patient selection and injection technique, these injections are a viable treatment option for patients with early symptomatic knee OA.…”
Section: Discussionmentioning
confidence: 99%
“…Specially, there is a decrease in concentration and molecular weight of HA on OA [5,6]. Hence, intraarticular viscosupplementation with HA may restore normal biochemical properties/ characteristics in various joint structures, resulting in improved pain control and function [7].…”
Section: Introductionmentioning
confidence: 99%
“…A HA+CS combination solution was subcutaneously injected to the repair area of the subjects in the treatment groups after the wound was closed. No substance was used in the control group since the saline solution might increase the formation of adhesion (22). The wound was sutured and then closed with a dressing, and free joint movements were permitted.…”
Section: Surgical Proceduresmentioning
confidence: 99%
“…5) e John W. Palmer della Columbia University di New York (47). Esso è stato sperimentato verso la fine degli anni Sessanta nei cavalli da corsa con artropatie post-traumatiche (48) e quindi introdotto in patologia umana da un gruppo di ricercatori, fra i quali spicca il nome di Endre A. Balasz (49,50). A distanza di oltre vent'anni, possiamo affermare che l'acido jaluronico mantiene un ruolo importante nella terapia locale delle reumoartropatie, soprattutto di quelle degenerative (51): lo scopo principale del trattamento, infatti, è quello di aumentare la viscosità del liquido sinoviale, diminuita nell' osteoartrosi proprio per la riduzione del suo contenuto in jaluronati.…”
Section: "Se Poi LI Funghi Degli Articoli Sono Da Gran Tempo Invecchiunclassified