Effect of Intra-operative Intra-arterial Thrombolysis on Long Term Clinical Outcomes in Patients with Acute Popliteal Artery Aneurysm Thrombosis

Comparison of popliteal artery aneurysm outcomes after open repair and endovascular repair: reducing post-operative type II endoleak and sac enlargement

“…Acute ischemia resulting from PAA thrombosis is associated with a high limb-threatening risk (30). When acute ischemia occurs, emergency PAA exclusion or resection plus autologous vein bypass is usually performed, which is still the standard procedure for PAA patients.…”

“…Schwarz et al introduced pre-operative intra-arterial thrombolysis in 1984 to improve the revascularization and patency of distal vessels (31). Dragas et al noted that CDT prior to surgery can reduce long-term major adverse limb events and provide overall survival benefits in selected patients with no risk of increasing major or lifethreatening bleeding complications (30). However, it should be noted that a review conducted in 2010 revealed that preoperative thrombolysis did not improve the limb salvage rate (32).…”

Update of the European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Acute Limb Ischaemia in Light of the COVID-19 Pandemic, Based on a Scoping Review of the Literature

“…Likewise, improved long term results when using intra-operative intra-arterial thrombolysis in patients with ALI and popliteal artery aneurysms (who were not COVID-19þ) were recently reported in a comparative study using propensity score matching (major adverse limb events 30% vs. 65%, p < .001). 45 To avoid any airway manipulation, regional anaesthesia might be preferable over general anaesthesia. Benefits of regional anaesthesia include preservation of respiratory function, and avoidance of aerosolisation and hence less viral transmission to staff members.…”

One Year on: Test Your Knowledge From February 2020

“…Which of the following is correct according to the results of this study? 5 A. MALE is reduced in the thrombolysis group.…”