Effect of intramolecular hydrogen bonding on biomimetic reactions by flavins

Abstract

Selected 6-and 7-carboxyflavins activate H 2 O 2 , oxidizing thioanisole to its sulfoxide. The greater reactivity of the 6-carboxyflavin derivatives are ascribed to the intramolecular hydrogen bonding between N(5) and the carboxyl group of the flavin system.

Absorption Spectral Studies on Naphthyl Pyridyl Pyrazole (NPP) in Mixed Solvent Systems

“…These changes are due to the result of physical intermolecular solute-solvent interaction forces (such as ion-dipole, dipole-dipole, dipole-induced dipole, hydrogen bonding, etc. ), which above all tend to alter the energy difference between ground and excite state of the absorbing species containing the chromophore [9][10][11][12][13][14] .…”