Effect of intranasal budesonide irrigations on intraocular pressure

Seiberling, Kristin; Chang, Dennis; Nyirady, Janice; Park, Francine; Church, Christopher A.

doi:10.1002/alr.21180

Cited by 36 publications

(42 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1021 No significant elevation of pressure was shown with an average duration of use of 6.3 months in 10 of the patients. A relatively low dose of active drug is probably delivered to the mucosa using irrigation systems although the exact exposure is undetermined at present.…”

Section: Viiie1 Crswnp Management:-saline (Spray and Irrigation)mentioning

confidence: 85%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

558

888

View full text Add to dashboard Cite

Background:The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods:Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results:The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AE-CRS), and pediatric RS. Conclusion:As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too o en the foundation upon which these recommendations are based is comprised of lowerlevel evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed. C 2016 ARS-AAOA, LLC. Key Words:rhinosinusitis; chronic rhinosinusitis; acute rhinosinusitis; recurrent acute rhinosinusitis; evidence-based medicine; systematic review; endoscopic sinus surgery List of Abbreviations Used

show abstract

Section: Viiie1 Crswnp Management:-saline (Spray and Irrigation)mentioning

confidence: 85%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

558

888

View full text Add to dashboard Cite

show abstract

“…Of these 19 included studies, 9 reported data outcome on IOP (3,6,11,13,(20)(21)(22)(23)(24) , 1 on lens opacity (25) , and 9 studies reported data on both IOP and lens opacity (14,(26)(27)(28)(29)(30)(31)(32)(33) . This then left 18 (94.7%) (3,6,11,13,14,(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33) studies on IOP, and 10 (55.6%) (14,(25)(26)(27)(28)(29)(30)(31)(32)(33) ) on lens opacity in clearly defined patient groups that could be used for comparison in this systematic review (14,...…”

Section: Included Studiesmentioning

confidence: 99%

“…This then left 18 (94.7%) (3,6,11,13,14,(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33) studies on IOP, and 10 (55.6%) (14,(25)(26)(27)(28)(29)(30)(31)(32)(33) ) on lens opacity in clearly defined patient groups that could be used for comparison in this systematic review (14,(26)(27)(28)(29)(30)(31)(32)(33) . The study characteristics of the 19 included manuscripts are described in Tables 4 and 5.…”

Section: Included Studiesmentioning

confidence: 99%

“…These studies included 10 RCTs (57.9%) (6,(20)(21)(22)(23)(26)(27)(28)(29)(30)(31) and one case-control study (1) .…”

Section: Intraocular Pressure and Incsmentioning

confidence: 99%

“…With their well-known anti-inflammatory properties, they provide relief for rhinitis symptoms, decongest airway oedema, restore nasal breathing, decrease mucus production and reduce the recurrence rates of upper airway inflammation (1,(4)(5)(6) . Therefore, INCS are recommended in many evidence-based guidelines, for the management of upper airway disease (7,8) .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Intranasal corticosteroids do not affect intraocular pressure or lens opacity: a systematic review of controlled trials

Ahmadi

Snidvongs

Kalish

et al. 2015

Rhin

View full text Add to dashboard Cite

Results: 665 articles were retrieved with 137 were considered for full-text review. Of these, 116 (85%) were literature reviews and two were case reports. 19 studies (10 RCTs, 1 case-control, 8 case series) were included for the qualitative review, of which 18 reported data on IOP and 10 on cataract/LO. None (n=0) of the 10 RCT reporting data on glaucoma or IOP demonstrated changes in IOP compared to control. Also none (n=0) of the 6 RCTs reporting cataract or lens opacity demonstrated changes compared to control. Conclusion:Data from studies with low levels of bias, do not demonstrate a clinically relevant impact of INCS on neither ocular pressure, glaucoma, lens opacity nor cataract formation.

show abstract

Editorial

Jacobs¹

2013

Int Forum Allergy Rhinol

View full text Add to dashboard Cite

Effect of intranasal budesonide irrigations on intraocular pressure

Abstract: Intranasal budesonide irrigations given for a period of at least 1 month do not appear to increase IOP.

Cited by 36 publications

References 13 publications

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Intranasal corticosteroids do not affect intraocular pressure or lens opacity: a systematic review of controlled trials

Editorial

Contact Info

Product

Resources

About