Effect of intraoperative infiltration with local anesthesia on the development of chronic pain after inguinal hernia repair: A randomized, triple-blinded, placebo-controlled trial

Kurmann, Anita; Fischer, Henning; Dell-Kuster, Salome; Rosenthal, Rachel; Audigé, Laurent; Schüpfer, G.; Metzger, Jürg; Honigmann, Philipp

doi:10.1016/j.surg.2014.07.008

Cited by 31 publications

(38 citation statements)

References 32 publications

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“…One of these three patients returned to the operating room for tack removal. While the exact cause of chronic pain following hernia repair remains difficult to ascertain, we hypothesized the pain may be secondary to tack fixation or mesh placement as has been suggested by others [15][16][17]. Nevertheless, the postoperative complications encountered were similar to what has previously been reported in conventional TEP suggesting the two-port technique is equally as safe as three-port TEP [12,14].…”

Section: Discussionmentioning

confidence: 57%

Two-port totally extraperitoneal inguinal hernia repair: a 10-year experience

Fuglestad

Waisbren

2015

Hernia

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Section: Discussionmentioning

confidence: 57%

Two-port totally extraperitoneal inguinal hernia repair: a 10-year experience

Fuglestad

Waisbren

2015

Hernia

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“…Nefopam reduces CPOP incidence after breast surgery 16 but fails to be effective after TKA 62 . Local infiltration of bupivacaine does not provide a meaningful reduction in CPOP after inguinal hernia surgery 66 , TKA 64 , or THA 64 . However, spinal or local infiltration anesthesia does reduce CPOP incidence following inguinal hernia repair in the presence of a COX inhibitor 27 and the addition of a COX inhibitor to an epidural reduces the incidence of CPOP following thoracic surgery 71 , but, following breast surgery, a COX inhibitor added to a paravertebral block has no effect on CPOP 46 .…”

Section: Discussionmentioning

confidence: 94%

“…A 2015 study failed to demonstrate any reduction in CPOP development from local infiltration of 20 mL 0.25% bupivacaine 66 , whereas, in 2016, Bugada et al . found that local infiltration or spinal anesthesia reduced CPOP incidence when patients also received postoperative ketorolac for 4 days 27 .…”

Section: Preventionmentioning

confidence: 98%

Chronic postoperative pain: recent findings in understanding and management

Correll

2017

F1000Res

112

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Chronic postoperative pain is a poorly recognized potential outcome from surgery. It affects millions of patients every year, with pain lasting for months to years, resulting in patient suffering and ensuing economic consequences. The operations with the highest incidence of chronic postoperative pain are amputations, thoracotomies, cardiac surgery, and breast surgery. Other risk factors include preoperative pain, psychological factors, demographics, and the intensity of acute postoperative pain. Attempts to prevent chronic postoperative pain have often led to debatable results. This article presents data from recently published studies examining the incidence, risk factors, mechanisms, treatment options, and preventive strategies for chronic postoperative pain in adults. In summary, many of the previously identified risk factors for chronic postoperative pain have been confirmed and some novel ones discovered, such as the importance of the trajectory of acute pain and the fact that catastrophizing may not always be predictive. The incidence of chronic postoperative pain hasn’t changed over time, and there is limited new information regarding an effective preventive therapy. For example, pregabalin may actually cause more harm in certain surgeries. Further research is needed to demonstrate whether multimodal analgesic techniques have the best chance of significantly reducing the incidence of chronic postoperative pain and to determine which combination of agents is best for given surgical types and different patient populations.

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“…This ‘chronic' time frame ranged between 1 and 36 months [63,64,65,66,67]. Second, some studies included the quantitative factor PI in their definition of CPIP, which was either expressed using descriptive terms [68,69,70,71,72,73,74,75], a visual analog scale (VAS) score, or a QOL score [31,76,77,78,79,80,81,82,83,84,85]. …”

Section: Resultsmentioning

confidence: 99%

“…Thirty-two studies (40%) had a validated assessment of both PI and QOL [11,14,19,20,22,24,29,31,34,38,40,41,43,45,48,53,54,56,58,60,62,65,67,73,74,76,84,86,87,88,89,90]; in 33 (41%) and 3 (4%) of the studies, respectively, there was only a validated assessment of PI [8,10,13,17,21,23,25,26,28,30,33,35,36,42,44,47,49,50,52,59,61,63,69,71,77,78,80,81,82,83,85] or QOL [46,51,57]. …”

Section: Resultsmentioning

confidence: 99%

Uniformity of Chronic Pain Assessment after Inguinal Hernia Repair: A Critical Review of the Literature

2016

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Background: Chronic postoperative inguinal pain (CPIP) is the most common long-term complication of inguinal hernia repair. As such procedures are routinely performed, CPIP can be considered a significant burden to global health care. Therefore, adequate preventative measures relevant to surgical practice are investigated. However, as no gold standard research approach is currently available, study and outcome measures differ between studies. The current review aims to provide a qualitative analysis of the literature to seek out if outcomes of CPIP are valid and comparable, facilitating recommendations on the best approach to preventing CPIP. Methods: A systematic review of recent studies investigating CPIP was performed, comprising studies published in 2007-2015. Study designs were analyzed regarding the CPIP definitions applied, the use of validated instruments, the availability of a baseline score, and the existence of a minimal follow-up of 12 months. Results: Eighty eligible studies were included. In 48 studies, 22 different definitions of CPIP were identified, of which the definition provided by the International Association for the Study of Pain was applied most often. Of the studies included, 53 (66%) used 33 different validated instruments to quantify CPIP. There were 32 studies (40%) that assessed both pain intensity (PI) and quality of life (QOL) with validated tools, 41% and 4% had a validated assessment of only PI or QOL, respectively, and 15% lacked a validated assessment. The visual analog scale and the Short Form 36 (SF36) were most commonly used for measuring PI (73%) and QOL (19%). Assessment of CPIP was unclear in 15% of the studies included. A baseline score was assessed in 45% of the studies, and 75% had a follow-up of at least 12 months. Conclusion: The current literature addressing CPIP after inguinal hernia repair has a variable degree of quality and lacks uniformity in outcome measures. Proper comparison of the study results to provide conclusive recommendations for preventive measures against CPIP therefore remains difficult. These findings reaffirm the need for a uniform and validated assessment with uniform reporting of outcomes to improve the burden that CPIP poses to a significant surgical patient population.

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Effect of intraoperative infiltration with local anesthesia on the development of chronic pain after inguinal hernia repair: A randomized, triple-blinded, placebo-controlled trial

Cited by 31 publications

References 32 publications

Two-port totally extraperitoneal inguinal hernia repair: a 10-year experience

Two-port totally extraperitoneal inguinal hernia repair: a 10-year experience

Chronic postoperative pain: recent findings in understanding and management

Uniformity of Chronic Pain Assessment after Inguinal Hernia Repair: A Critical Review of the Literature

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