Effect of Intraoperative Radiocolloid Injection on Sentinel Lymph Node Biopsy in Patients with Breast Cancer

Stell, Virginia H.; Flippo‐Morton, Teresa S.; Norton, H. James; White, Richard L.

doi:10.1245/s10434-009-0537-y

Cited by 8 publications

(4 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Stell et al compared the incidence of positive sentinel lymph nodes between 102 patients with preoperative injection of radiocolloid and that of 112 patients with intraoperative injection. The 2 groups had equivalent tumor characteristics and incidence of positive sentinel lymph nodes, 20.6% for preoperative injection versus 19.6% for intraoperative injection (14). The VCUHS study also shows no statistical difference in the overall positive sentinel node biopsy rate between preoperative injection (25.6%) and intraoperative injection (26.4%).…”

Section: Discussionmentioning

confidence: 84%

Intraoperative Injection of Radiocolloid for Sentinel Node Biopsy in Breast Cancer

O’Connor

Shoemaker

et al. 2013

Journal of Nuclear Medicine Technology

View full text Add to dashboard Cite

The sentinel lymph node identification rate of 94.6% for the intraoperative injection group was similar to other published sentinel lymph node identification rates (96%-100%). The positive sentinel lymph node rate was also comparable to that of published series. Intraoperative injection of radiocolloid for axillary sentinel node biopsy appears equivalent to preoperative injection and is a less painful experience for breast cancer patients.

show abstract

Section: Discussionmentioning

confidence: 84%

Intraoperative Injection of Radiocolloid for Sentinel Node Biopsy in Breast Cancer

O’Connor

Shoemaker

et al. 2013

Journal of Nuclear Medicine Technology

View full text Add to dashboard Cite

show abstract

“…Johnson [6] reported on 775 IRCI; the SNIDR remained excellent at 98.6%. Stell [7] compared the incidence of positive sentinel lymph nodes between 102 patients with PRCI and that of 112 patients with IRCI. Both groups had equivalent tumor characteristics and incidence of positive sentinel lymph nodes: 20.6% for PRCI versus 19.6% for IRCI.…”

Section: Discussionmentioning

confidence: 99%

Intraoperative radiocolloid injection for sentinel node biopsy postneoadjuvant chemotherapy

Shoemaker

O’Connor

et al. 2015

Journal of Surgical Research

View full text Add to dashboard Cite

“…All regimens followed NCCN guidelines or were IRB‐approved neo‐adjuvant protocols. SLN biopsy was performed using isosulfan blue dye (5 cc) and 500 μCi of filtered dermally injected technetium sulfur colloid (0.5 cc) (6).…”

Section: Methodsmentioning

confidence: 99%

“…Recurrence and follow‐up information was collected for this neo‐adjuvant (NEO) group. Information from a previously collected dataset (6) of non‐neo‐adjuvant (NON) patients with breast cancer who successfully underwent SLN biopsies from June 1, 2007 to May 31, 2008 was compared with the NEO group for demographics, tumor characteristics, and SLN biopsy results. Twelve cases of ductal carcinoma in situ from the original NON dataset were excluded from the current analysis.…”

Section: Methodsmentioning

confidence: 99%

Sentinel Lymph Node Biopsy After Neo-adjuvant Chemotherapy in Breast Cancer

et al. 2010

Self Cite

View full text Add to dashboard Cite

The timing of sentinel node biopsy in the setting of neo-adjuvant chemotherapy for breast cancer is controversial. Sentinel node biopsy performed after neo-adjuvant chemotherapy may save patients with a nodal response the morbidity of an axillary lymph node dissection. A retrospective review of prospectively collected data compared sentinel node biopsies performed after patients had received neo-adjuvant chemotherapy with patients who had not received neo-adjuvant chemotherapy. Demographic factors, tumor characteristics, and the results of the sentinel node biopsies and completion lymph node dissections (when applicable) were compared. A total of 231 axillary procedures (224 patients) were evaluated. The patients who received neo-adjuvant chemotherapy (NEO; N=52) were younger, had higher grade tumors, were more likely to have a mastectomy, and were more likely to have ER-negative and HER-2/neu positive tumors than the patients who did not receive neo-adjuvant chemotherapy (NON; N=179). The mean clinical tumor size in the neo-adjuvant group was 4.5cm (±1.8) prior to chemotherapy; the post-chemotherapy pathologic size was 1.4cm (±1.3). A sentinel node was identified in all cases. There were no significant differences between the groups in the mean number of sentinel nodes removed (NEO=3.3; NON=3.1; p=0.545), the percentage of positive axillae (NEO=24%; NON=21%; p=0.776) or the mean number of positive sentinel nodes (NEO=1.3; NON=1.5; p=0.627). There was no difference in the percentage of completion lymph node dissections with additional positive nodes (NEO=20%; NON=35%; p=0.462); there was a difference in the number of nodes removed in the completion lymph node dissections (mean NEO=12.0; NON=16.4; p=0.047). Sentinel node biopsy performed after neo-adjuvant chemotherapy appears to be an oncologically sound procedure and may save some patients the morbidity of a complete lymph node dissection.

show abstract

Effect of Intraoperative Radiocolloid Injection on Sentinel Lymph Node Biopsy in Patients with Breast Cancer

Abstract: There are no significant differences in the principal results of SLN biopsy between PO and IO injection methods. Dermal radiocolloid injection after induction of anesthesia seems to be an oncologically sound procedure and may be a preferable technique.

Cited by 8 publications

References 20 publications

Intraoperative Injection of Radiocolloid for Sentinel Node Biopsy in Breast Cancer

Intraoperative Injection of Radiocolloid for Sentinel Node Biopsy in Breast Cancer

Intraoperative radiocolloid injection for sentinel node biopsy postneoadjuvant chemotherapy

Sentinel Lymph Node Biopsy After Neo-adjuvant Chemotherapy in Breast Cancer

Contact Info

Product

Resources

About