Effect of irradiation with monochromatic visible light on cAMP content in Chinese hamster fibroblasts

Low‐energy laser irradiation promotes synovial fibroblast proliferation by modulating p15 subcellular localization

“…In addition, He-Ne irradiation on melanoma cell line induced an increase in mitochondrial membrane potential, ATP, and cAMP via enhanced cytochrome c oxidase activity [8]. Karu et al [21] reported that the effect of light irradiation on cAMP content using light at several wavelengths was different according to the wavelength and time points. Furthermore, light irradiation induces a decrease in cAMP levels in rod cells [22,23].…”

“…On the other hand, cAMP has a variety of effects on cell proliferation, that is, on inhibiting [15][16][17][18] or stimulating [19,20] cell growth. It is known that LELI brings about increased [8,21] or decreased [22,23] cAMP levels, which influence the cell cycle by inducing CKIs [15][16][17][18].…”

Effects of low intensity infrared laser radiation on the water transport in the isolated toad urinary bladder

“…It is known that several cell membrane enzymes are involved actively in photosignal transduction such as pump Na þ , K þ -ATPase, Na þ /H þ antiporter, and enzymes controlling 3 0 5 0 -cAMP level in the cells [2,3]. This may have an effect on membrane permeability transport, inducing changes in the cellular homeostasis parameters [24].…”

“…Depending on the radiation intensity, several changes can occur in living substances, such as an alteration in molecular structure, ionization, rupture of chemical bonds, among others. It has been shown that laser radiation increases adenosine triphosphate (ATP), 3 0 5 0 -cyclic adenosine monophosphate (3 0 5 0 -cAMP) production, nucleic acid synthesis, and cell division, among others effects [2][3][4]. Basically, two sorts of reactions can be distinguished in the laser action mechanism: primary reactions (light-induced) and secondary reactions (dark-reactions).…”

Effects of 810-nm Laser on Murine Bone-Marrow-Derived Dendritic Cells

“…This phenomenon was thought to be because of blockage of phosphorylation of p38 mitogen-activated protein kinase (MAPK) by increased cAMP levels, but the NF-kB binding to the IL-12 promoter was not affected. It should be noted that there are several papers [38][39][40] from multiple different laboratories that show that cellular levels of cAMP are increased by in vitro LLLT.…”