Effect of kangaroo mother care in the management of low birth weight babies one year randomized controlled trial at NRI hospital

Bhavana, D. Sai; Boppana, Lakshmi; Sruthi, T.; Kumari, P. Kantha

doi:10.17511/ijpr.2016.i08.01

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Of the 3458 records identified from the database and bibliographic searches, 314–6 9–35 studies enrolling 15 559 infants were included in the review (figure 1); 25 studies were conducted in LMIC (two from multiple countries5 14 while seven were conducted in high-income countries12 20 24 26 29 30 34 (Appendix). Twenty-seven studies compared KMC with conventional care, while four compared early with late initiation of KMC 5 6 24 25.…”

Section: Resultsmentioning

confidence: 99%

Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis

Sivanandan

Sankar

2023

BMJ Glob Health

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ImportanceThe Cochrane review (2016) on kangaroo mother care (KMC) demonstrated a significant reduction in the risk of mortality in low birth weight infants. New evidence from large multi-centre randomised trials has been available since its publication.ObjectiveOur systematic review compared the effects of KMC vs conventional care and early (ie, within 24 hours of birth) vs late initiation of KMC on critical outcomes such as neonatal mortality.MethodsEight electronic databases, including PubMed®, Embase, and Cochrane CENTRAL, from inception until March 2022, were searched. All randomised trials comparing KMC vs conventional care or early vs late initiation of KMC in low birth weight or preterm infants were included.Data extraction and synthesisThe review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered with PROSPERO.Main outcomes and measuresThe primary outcome was mortality during birth hospitalization or 28 days of life. Other outcomes included severe infection, hypothermia, exclusive breastfeeding rates, and neurodevelopmental impairment. Results were pooled using fixed-effect and random-effects meta-analyses in RevMan 5.4 and Stata 15.1 (StataCorp, College Station, TX).ResultsIn total, 31 trials with 15 559 infants were included in the review; 27 studies compared KMC with conventional care, while four compared early vs late initiation of KMC. Compared with conventional care, KMC reduces the risks of mortality (relative risk (RR) 0.68; 95% confidence interval (CI) 0.53 to 0.86; 11 trials, 10 505 infants; high certainty evidence) during birth hospitalisation or 28 days of age and probably reduces severe infection until the latest follow-up (RR 0.85, 95% CI 0.79 to 0.92; nine trials; moderate certainty evidence). On subgroup analysis, the reduction in mortality was noted irrespective of gestational age or weight at enrolment, time of initiation, and place of initiation of KMC (hospital or community); the mortality benefits were greater when the daily duration of KMC was at least 8 hours per day than with shorter-duration KMC. Studies comparing early vs late-initiated KMC demonstrated a reduction in neonatal mortality (RR 0.77, 95% CI 0.66 to 0.91; three trials, 3693 infants; high certainty evidence) and a probable decrease in clinical sepsis until 28-days (RR 0.85, 95% CI 0.76 to 0.96; two trials; low certainty evidence) following early initiation of KMC.Conclusions and relevanceThe review provides updated evidence on the effects of KMC on mortality and other critical outcomes in preterm and low birth weight infants. The findings suggest that KMC should preferably be initiated within 24 hours of birth and provided for at least 8 hours daily.

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Section: Resultsmentioning

confidence: 99%

Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis

Sivanandan

Sankar

2023

BMJ Glob Health

View full text Add to dashboard Cite

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Kangaroo mother care for preterm or low birth weight infants: A systematic review and meta-analysis

Sivanandan

Sankar

2022

Preprint

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ImportanceThe Cochrane review (2016) on kangaroo mother care (KMC) demonstrated a significant reduction in the risk of mortality in low birth weight (LBW) infants. New evidence from large multi-center randomized trials has been available since its publication.ObjectiveThe objective of the systematic review was to compare the effects of KMC vs. conventional care and early (i.e., within 24 hours of birth) vs. late initiation of KMC on critical outcomes such as neonatal mortality.MethodsEight electronic databases, including PubMed, Embase, and Cochrane CENTRAL, until March 2022, were searched. All randomized trials comparing KMC versus conventional care or early vs. late initiation of KMC in LBW or preterm infants were included.Data extraction and synthesisThe review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered with PROSPERO.Main outcomes and measuresThe primary outcome was mortality by 28 days of life. Other outcomes included severe infection, hypothermia, exclusive breastfeeding rates, and neurodevelopmental impairment. Results were pooled using fixed-effect and random-effects meta-analyses in RevMan 5.4 or Stata 15.1 (StataCorp, College Station, TX).ResultsIn total, 31 trials with 15,559 infants were included in the review; 27 studies compared KMC with conventional care, while 4 compared early vs. late initiation of KMC. Compared to conventional care, KMC significantly reduced the risks of mortality (relative risk [RR] 0.68; 95% CI 0.53 to 0.86; 11 trials, 10505 infants; high certainty evidence) at discharge or 28 days of age and severe infection till the latest follow-up (RR 0.85, 95% CI 0.79 to 0.92; 9 trials; moderate certainty evidence). On subgroup analysis, KMC provided for a duration of at least 8 hours per day had more significant benefits compared to lesser duration KMC. Studies comparing early vs. late-initiated KMC demonstrated a significant reduction in neonatal mortality (RR 0.77, 95% CI 0.66 to 0.91; 3 trials, 3693 infants; high certainty evidence) and clinical sepsis till 28-days (RR 0.85, 95% CI 0.76 to 0.96; 2 trials; low certainty evidence) favoring early initiation of KMC.Conclusions and RelevanceThe review provides updated evidence on the effects of KMC on mortality and other critical outcomes in low birth weight infants. The findings suggest that KMC should preferably be initiated within 24 hours of birth and provided for at least 8 hours daily.

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Effect of kangaroo mother care in the management of low birth weight babies one year randomized controlled trial at NRI hospital

Cited by 2 publications

References 8 publications

Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis

Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis

Kangaroo mother care for preterm or low birth weight infants: A systematic review and meta-analysis

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