“…Likewise, we recently demonstrated that the NMDAR antagonist ketamine induces a significant reduction of MMN, but not of N1, in healthy volunteers (Umbricht et al, 2000). Similarly, ketamine and other NMDAR antagonists significantly reduced MMNm (the magnetic counterpart of MMN) and MMN, respectively, in healthy volunteers (Jääskeläinen et al, 1995a(Jääskeläinen et al, , b, 1996Kreitschmann-Andermahr et al, 2001;Pang and Fowler, 1999). In addition, subanesthetic doses of ketamine induce a pattern of deficits in AX-CPT performance in healthy volunteers that is characterized by a specific increase of context-dependent (BX) errors and closely resembles the deficits observed in schizophrenia (Umbricht et al, 2000).…”