Effect of ligands in two-photon excited luminescence of organometallic iridium complexes

Sekiguchi, Yasuhiro; Yamashita, Takashi; Vácha, Martin

doi:10.1016/j.jlumin.2007.11.046

Cited by 7 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The output intensity of the two‐photon‐excited fluorescence was linearly dependent on the square of the input laser power (Figure S22 in the Supporting Information), thereby confirming nonlinear TPA. The TPA cross section of our probes is moderate compared with those of other iridium(III) complexes measured with a two‐photon laser‐induced phosphorescence method reported in the literature …”

Section: Resultsmentioning

confidence: 67%

“…complexes measured with at wo-photon laser-inducedp hosphorescence methodr eported in the literature. [37][38][39][40][41][42][43][44]…”

Section: Two-photon Absorption (Tpa) Cross Sectionsmentioning

confidence: 99%

“…[22][23][24]36] More importantly,i ridium(III)c omplexes have been developed as two-photon probes. [36][37][38][39][40][41][42][43][44][45] Herein, we designed ands ynthesized as eries of two-photon phosphorescent iridium(III) complexes for mitochondria imaging and tracking under hypoxiaw ith high sensitivity and specificity. We introduced two anthraquinone groups as ancillary ligands to the iridium(III) complexes( Figure 1).…”

Section: Introductionmentioning

confidence: 99%

“…We demonstrated previously that some iridium(III) complexes possessed high specificity for mitochondria and could be used for mitochondrial imaging and tracking without damaging mitochondrial membranes . More importantly, iridium(III) complexes have been developed as two‐photon probes . Herein, we designed and synthesized a series of two‐photon phosphorescent iridium(III) complexes for mitochondria imaging and tracking under hypoxia with high sensitivity and specificity.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Iridium(III) Anthraquinone Complexes as Two‐Photon Phosphorescence Probes for Mitochondria Imaging and Tracking under Hypoxia

Sun

Chen

Kuang

et al. 2016

Chemistry A European J

View full text Add to dashboard Cite

In the present study, four mitochondria-specific and two-photon phosphorescence iridium(III) complexes, Ir1-Ir4, were developed for mitochondria imaging in hypoxic tumor cells. The iridium(III) complex has two anthraquinone groups that are hypoxia-sensitive moieties. The phosphorescence of the iridium(III) complex was quenched by the functions of the intramolecular quinone unit, and it was restored through two-electron bioreduction under hypoxia. When the probes were reduced by reductase to hydroquinone derivative products under hypoxia, a significant enhancement in phosphorescence intensity was observed under one- (λ=405 nm) and two-photon (λ=720 nm) excitation, with a two-photon absorption cross section of 76-153 GM at λ=720 nm. More importantly, these probes possessed excellent specificity for mitochondria, which allowed imaging and tracking of the mitochondrial morphological changes in a hypoxic environment over a long period of time. Moreover, the probes can visualize hypoxic mitochondria in 3D multicellular spheroids and living zebrafish through two-photon phosphorescence imaging.

show abstract

Section: Resultsmentioning

confidence: 67%

“…complexes measured with at wo-photon laser-inducedp hosphorescence methodr eported in the literature. [37][38][39][40][41][42][43][44]…”

Section: Two-photon Absorption (Tpa) Cross Sectionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Iridium(III) Anthraquinone Complexes as Two‐Photon Phosphorescence Probes for Mitochondria Imaging and Tracking under Hypoxia

Sun

Chen

Kuang

et al. 2016

Chemistry A European J

View full text Add to dashboard Cite

show abstract

“…1 By contrast, far fewer metalbased chromophores have been investigated even though they possess attractive chemical and photophysical properties. [12][13][14][15][16] Second and third row transition metal oligopyridyl complexes lend themselves particularly well to non-linear processes. 17, 18 For instance, the rich photochemistry of the charge transfer excited triplet states of Ir (and Ru) complexes with an N 6 coordination sphere gives rise to long phosphorescent lifetimes in aerated fluid solution in the microsecond time domain.…”

Section: Introductionmentioning

confidence: 99%

Two-photon luminescence from polar bis-terpyridyl-stilbene derivatives of Ir(iii) and Ru(ii)

et al. 2010

View full text Add to dashboard Cite

Four structurally related iridium(III) and ruthenium(II) complexes bearing two polar terpyridyl-stilbene derived chromophores 4-(4-{2-[4-(methoxy)phenyl]ethenyl}phenyl)-2,2'-6',2''-terpyridine (ttpyeneanisole) and 4-(4-{2-[phenyl]ethenyl}phenyl)-2,2'-6',2''-terpyridine (tpystilbene) have been synthesised and characterised in the solid state and in solution. In the solid state, the dihedral angle subtending the pyridyl and tolyl groups of 27.1° in the Ir(III) complex [Ir(ttpyeneanisole)(2)]·3PF(6) is more acute than in the Ru(II) derivative [Ru(tpystilbene)(2)]·2PF(6) (35.5°), indicating the presence of a greater degree of π-delocalisation across the terpyridine unit in the former compound. Their luminescence properties in fluid solution have been investigated following both resonant and non-resonant excitation. We have shown that each of the complexes undergoes two-photon excitation when excited in the near infrared (740 to 820 nm), with two-photon absorption cross sections in the range 11-67 × 10(-50) cm(4) s photon(-1). The larger cross sections for the Ir(III) complexes reflect the differences observed in the solid state. This work therefore demonstrates that such complexes are promising as luminescent markers for 3D imaging and illustrates that simple functionalisation of the chromophores and the choice of metal can lead to marked enhancements in the two-photon cross sections (σ(2)) compared to those of simpler heteroleptic polypyridyl based derivatives.

show abstract

A mitochondrial targeted two-photon iridium(III) phosphorescent probe for selective detection of hypochlorite in live cells and in vivo

et al. 2015

View full text Add to dashboard Cite

Effect of ligands in two-photon excited luminescence of organometallic iridium complexes

Cited by 7 publications

References 7 publications

Iridium(III) Anthraquinone Complexes as Two‐Photon Phosphorescence Probes for Mitochondria Imaging and Tracking under Hypoxia

Iridium(III) Anthraquinone Complexes as Two‐Photon Phosphorescence Probes for Mitochondria Imaging and Tracking under Hypoxia

Two-photon luminescence from polar bis-terpyridyl-stilbene derivatives of Ir(iii) and Ru(ii)

A mitochondrial targeted two-photon iridium(III) phosphorescent probe for selective detection of hypochlorite in live cells and in vivo

Contact Info

Product

Resources

About